The registry is an European, multicentre, prospective and longitudinal study which follows a cohort of children born to mothers with antiphospholipid syndrome (APS). In this article we report preliminary results obtained from 138 mothers and 141 babies (three twin pregnancies). At birth, 16.3% of neonates were less than 37 weeks of gestation and 17% were low birth weight; in addition, 11.3% of neonates were small for gestational age. No cases of neonatal thrombosis were observed. During follow-up period five children showed behavioral abnormalities. A long term clinical follow-up will be necessary to evaluate the neuropsychological development of these children.
Motta, M., Lachassinne, E., Boffa, M., Tincani, A., Avcin, T., De Carolis, S., Aurousseau, M., Le, T., P,, Lojacono, A., De Carolis, M. P., Chirico, G., European registry of infants born to mothers with antiphospholipid syndrome: preliminary results., <<MINERVA PEDIATRICA>>, 2010; (Giugno): 25-27 [http://hdl.handle.net/10807/20544]
European registry of infants born to mothers with antiphospholipid syndrome: preliminary results.
Motta, Mario;De Carolis, Sara;De Carolis, Maria Pia;
2010
Abstract
The registry is an European, multicentre, prospective and longitudinal study which follows a cohort of children born to mothers with antiphospholipid syndrome (APS). In this article we report preliminary results obtained from 138 mothers and 141 babies (three twin pregnancies). At birth, 16.3% of neonates were less than 37 weeks of gestation and 17% were low birth weight; in addition, 11.3% of neonates were small for gestational age. No cases of neonatal thrombosis were observed. During follow-up period five children showed behavioral abnormalities. A long term clinical follow-up will be necessary to evaluate the neuropsychological development of these children.
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