IRIS PubliCatt
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EnglishPatients with inflammatory bowel disease (IBD) have an increased risk of thrombotic complications. Moreover, a hypercoagulable state has been hypothesized as a contributing factor in the pathogenesis of IBD. Recently, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor for thromboembolic disease. We aimed to evaluate the prevalence of hyperhomocysteinemia in patients with IBD and to investigate the contribution of genetic defects in the enzymes involved in homocysteine (Hcy) metabolism and vitamin status in determining increased levels of plasma total Hcy (tHcy).
Papa, A., De Stefano, V., Danese, S., Chiusolo, P., Persichilli, S., Casorelli, I., Zappacosta, B., Giardina, B., Gasbarrini, A., Leone, G., Gasbarrini, G. B., Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease, <<THE AMERICAN JOURNAL OF GASTROENTEROLOGY>>, 2001; 96 (9): 2677-2682. [doi:10.1111/j.1572-0241.2001.04127.x] [http://hdl.handle.net/10807/20523]
| Autori: | ||
| Titolo: | Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.1572-0241.2001.04127.x | |
| Data di pubblicazione: | 2001 | |
| Abstract: | Patients with inflammatory bowel disease (IBD) have an increased risk of thrombotic complications. Moreover, a hypercoagulable state has been hypothesized as a contributing factor in the pathogenesis of IBD. Recently, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor for thromboembolic disease. We aimed to evaluate the prevalence of hyperhomocysteinemia in patients with IBD and to investigate the contribution of genetic defects in the enzymes involved in homocysteine (Hcy) metabolism and vitamin status in determining increased levels of plasma total Hcy (tHcy). | |
| Lingua: | Inglese | |
| Rivista: | ||
| Citazione: | Papa, A., De Stefano, V., Danese, S., Chiusolo, P., Persichilli, S., Casorelli, I., Zappacosta, B., Giardina, B., Gasbarrini, A., Leone, G., Gasbarrini, G. B., Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease, <<THE AMERICAN JOURNAL OF GASTROENTEROLOGY>>, 2001; 96 (9): 2677-2682. [doi:10.1111/j.1572-0241.2001.04127.x] [http://hdl.handle.net/10807/20523] | |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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