Amiodarone is a drug commonly used to treat and prevent cardiac arrhythmias, but it is often associated with several adverse effects, the most serious of which is pulmonary toxicity. A 79-year-old man presented with respiratory failure due to interstitial pneumonia during the COVID-19 pandemic. The viral etiology was nevertheless excluded by repeated nasopharyngeal swabs and serological tests and the final diagnosis was amiodarone-induced organizing pneumonia. The clinical and computed tomography findings improved after amiodarone interruption and steroid therapy. Even during a pandemic, differential diagnosis should always be considered and pulmonary toxicity has to be taken into account in any patient taking amiodarone and who has new respiratory symptoms.
Cappannoli, L., Telesca, A., Scacciavillani, R., Petrolati, E., Smargiassi, A., Rabini, A., Massetti, M., Crea, F., Aspromonte, N., A nontrivial differential diagnosis in COVID-19 pandemic: A case report and literary review of amiodarone-induced interstitial pneumonia, <<FUTURE CARDIOLOGY>>, 2021; 17 (6): 991-997. [doi:10.2217/fca-2020-0168] [http://hdl.handle.net/10807/204499]
A nontrivial differential diagnosis in COVID-19 pandemic: A case report and literary review of amiodarone-induced interstitial pneumonia
Cappannoli, Luigi;Telesca, Alessandro;Scacciavillani, Roberto;Petrolati, Edoardo;Smargiassi, Andrea;Rabini, Alessia;Massetti, Massimo;Crea, Filippo;Aspromonte, Nadia
2021
Abstract
Amiodarone is a drug commonly used to treat and prevent cardiac arrhythmias, but it is often associated with several adverse effects, the most serious of which is pulmonary toxicity. A 79-year-old man presented with respiratory failure due to interstitial pneumonia during the COVID-19 pandemic. The viral etiology was nevertheless excluded by repeated nasopharyngeal swabs and serological tests and the final diagnosis was amiodarone-induced organizing pneumonia. The clinical and computed tomography findings improved after amiodarone interruption and steroid therapy. Even during a pandemic, differential diagnosis should always be considered and pulmonary toxicity has to be taken into account in any patient taking amiodarone and who has new respiratory symptoms.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.