Porokeratosis of Mibelli is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a keratotic wall. We report a case of a giant verrucous porokeratosis of Mibelli mimicking psoriasis that developed in a patient with psoriasis and therefore went unrecognized for a long time. Histologically the lesion combined features of porokeratosis at the periphery and of psoriasis at its center, a picture recently described as "psoriasis encircled by porokeratosis." The possible pathogenetic relationship between psoriasis and the development of porokeratosis is also discussed.
De Simone, C., Paradisi, A., Massi, G., Proietti, I., Capponi, A., Amerio, P., Capizzi, R., Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis, <<JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY>>, 2007; 57 (4): 665-668. [doi:10.1016/j.jaad.2007.03.020] [http://hdl.handle.net/10807/20385]
Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis
De Simone, Clara;Paradisi, Andrea;Massi, Guido;Proietti, Ilaria;Capponi, Angela;Capizzi, Rodolfo
2007
Abstract
Porokeratosis of Mibelli is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a keratotic wall. We report a case of a giant verrucous porokeratosis of Mibelli mimicking psoriasis that developed in a patient with psoriasis and therefore went unrecognized for a long time. Histologically the lesion combined features of porokeratosis at the periphery and of psoriasis at its center, a picture recently described as "psoriasis encircled by porokeratosis." The possible pathogenetic relationship between psoriasis and the development of porokeratosis is also discussed.
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