Purpose: To report a case of multiple superior quadrant intraretinal haemorrhages in post-COVID-19 patient. Case description: A 58-year-old male with a history of coronary artery disease and hypertension, presented with multiple superior quadrant intraretinal haemorrhages in the superonasal quadrant of the left eye 1 month after hospitalization for COVID-19. The right eye was normal. During his 10-day stay, he was treated with hydroxychloroquine, lopinavir + ritonavir, ceftriaxone, and his pre-existing antiplatelet therapy. During hospitalization, a complete medical work up showed an anomalous increase in D-dimer. He did not require intensive care support. Conclusions: In this report, we focused on the origin of retinal bleeding in a post COVID-19 patient, likely due to a focal occlusion of a vessel. Considering the nature of SARS-CoV-2 infection, we hypothesize that retinal haemorrhages were caused by a combination of factors including the patient’s antiplatelet therapy and the thrombotic microvascular injury caused by the virus.

Savastano, M. C., Culiersi, C., Savastano, A., Gambini, G., Caporossi, T., Rizzo, S., Focal superior quadrant haemorrhages in post COVID-19 patient: A target for personalized medicine, <<EUROPEAN JOURNAL OF OPHTHALMOLOGY>>, 2021; (giugno): 11206721211021296-N/A. [doi:10.1177/11206721211021296] [http://hdl.handle.net/10807/201412]

Focal superior quadrant haemorrhages in post COVID-19 patient: A target for personalized medicine

Savastano, M. C.;Culiersi, C.;Savastano, A.;Gambini, G.;Caporossi, T.;Rizzo, S.
2021

Abstract

Purpose: To report a case of multiple superior quadrant intraretinal haemorrhages in post-COVID-19 patient. Case description: A 58-year-old male with a history of coronary artery disease and hypertension, presented with multiple superior quadrant intraretinal haemorrhages in the superonasal quadrant of the left eye 1 month after hospitalization for COVID-19. The right eye was normal. During his 10-day stay, he was treated with hydroxychloroquine, lopinavir + ritonavir, ceftriaxone, and his pre-existing antiplatelet therapy. During hospitalization, a complete medical work up showed an anomalous increase in D-dimer. He did not require intensive care support. Conclusions: In this report, we focused on the origin of retinal bleeding in a post COVID-19 patient, likely due to a focal occlusion of a vessel. Considering the nature of SARS-CoV-2 infection, we hypothesize that retinal haemorrhages were caused by a combination of factors including the patient’s antiplatelet therapy and the thrombotic microvascular injury caused by the virus.
Inglese
Savastano, M. C., Culiersi, C., Savastano, A., Gambini, G., Caporossi, T., Rizzo, S., Focal superior quadrant haemorrhages in post COVID-19 patient: A target for personalized medicine, <<EUROPEAN JOURNAL OF OPHTHALMOLOGY>>, 2021; (giugno): 11206721211021296-N/A. [doi:10.1177/11206721211021296] [http://hdl.handle.net/10807/201412]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/201412
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