Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.

Arcadi, A., Cacchi, S., Fabrizi, G., Goggiamani, A., Iazzetti, A., Marinelli, F., 2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions, <<CHEM INFORM>>, 2013; 44 (22): no-no. [doi:10.1039/c2ob27125g] [http://hdl.handle.net/10807/200814]

2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions

Iazzetti, Antonia;
2013

Abstract

Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.
Inglese
Arcadi, A., Cacchi, S., Fabrizi, G., Goggiamani, A., Iazzetti, A., Marinelli, F., 2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions, <<CHEM INFORM>>, 2013; 44 (22): no-no. [doi:10.1039/c2ob27125g] [http://hdl.handle.net/10807/200814]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/200814
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