Purpose:To assess by cardiac-MR the prevalence of myocardial alterations in arrhythmic patients. Materials and methods:43 patients with non ischemic ventricular arrhythmias. Premature ventricular complexes had left bundle branch block morphology (LBBB) in 29 cases, in 7 a right bundle branch block contour (RBBB) and 7 had polymorphic patterns(PV). US was negative in 78.4% of patients, while CMR was negative in only 13% of patients. Studies were performed on a 1.5 MR scanner with Cine sequences (Fastcard or FIESTA), bb-FSE and IR-prep FGRE 15 minutes after injection of 0.2 mmol/Kg of Gd-DTPA. Results: CMR found a high prevalence of morphological, signal intensity and functional myocardial abnormalities. RV dilatation was found in 85% of patients with PV arrhythmias, 48.3% of patients with LBBB morphology, 12.5% of patients with RBBB morphology. LV dilatation was present in 28.6%, 25% and 24.1% of patients with LBBB, PV and RBBB type arrhythmias respectively. RV wall motion abnormalities were identified in 50% and 36.7% of patients with PV and LBBB pattern respectively while LV motion abnormalities in 25% and 10.3%. Free wall RV signal/thickness abnormalities were found in 23.3% of patients; LV signal abnormalities were found in 11.6% of patients.Seven patients underwent myocardial biopsy: 5 positive for myocarditis, 1 positive for ARVD, one had a negative biopsy. Conclusions: In patients with primary ventricular arrhythmias MR documented high prevalence (87%) of morphological, signal intensity and wall motion abnormalities even with negative echocardiogram.

Bernardini, A., Meduri, A., Natale, L., Liguori, C., Fenici, R., Brisinda, D., Bonomo, L., CMR evaluation in patients with high grade ventricular arrhythmias, Abstract de <<12th Annual SCMR Scientific Sessions>>, (Orlando, 29-January 01-February 2009 ), <<JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE>>, 2009; 11 (Suppl 1): P205-P205 [http://hdl.handle.net/10807/20050]

CMR evaluation in patients with high grade ventricular arrhythmias

Bernardini, Antonio;Meduri, Agostino;Natale, Luigi;Liguori, Carlo;Fenici, Riccardo;Brisinda, Donatella;Bonomo, Lorenzo
2009

Abstract

Purpose:To assess by cardiac-MR the prevalence of myocardial alterations in arrhythmic patients. Materials and methods:43 patients with non ischemic ventricular arrhythmias. Premature ventricular complexes had left bundle branch block morphology (LBBB) in 29 cases, in 7 a right bundle branch block contour (RBBB) and 7 had polymorphic patterns(PV). US was negative in 78.4% of patients, while CMR was negative in only 13% of patients. Studies were performed on a 1.5 MR scanner with Cine sequences (Fastcard or FIESTA), bb-FSE and IR-prep FGRE 15 minutes after injection of 0.2 mmol/Kg of Gd-DTPA. Results: CMR found a high prevalence of morphological, signal intensity and functional myocardial abnormalities. RV dilatation was found in 85% of patients with PV arrhythmias, 48.3% of patients with LBBB morphology, 12.5% of patients with RBBB morphology. LV dilatation was present in 28.6%, 25% and 24.1% of patients with LBBB, PV and RBBB type arrhythmias respectively. RV wall motion abnormalities were identified in 50% and 36.7% of patients with PV and LBBB pattern respectively while LV motion abnormalities in 25% and 10.3%. Free wall RV signal/thickness abnormalities were found in 23.3% of patients; LV signal abnormalities were found in 11.6% of patients.Seven patients underwent myocardial biopsy: 5 positive for myocarditis, 1 positive for ARVD, one had a negative biopsy. Conclusions: In patients with primary ventricular arrhythmias MR documented high prevalence (87%) of morphological, signal intensity and wall motion abnormalities even with negative echocardiogram.
2009
Inglese
Bernardini, A., Meduri, A., Natale, L., Liguori, C., Fenici, R., Brisinda, D., Bonomo, L., CMR evaluation in patients with high grade ventricular arrhythmias, Abstract de <<12th Annual SCMR Scientific Sessions>>, (Orlando, 29-January 01-February 2009 ), <<JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE>>, 2009; 11 (Suppl 1): P205-P205 [http://hdl.handle.net/10807/20050]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/20050
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact