Introduction: The SARS CoV-2 pandemic still generates a very high number of affected patients and a significant mortality rate. It is essential to establish objective criteria to stratify COVID-19 death risk. Frailty has been identified as a potential determinant of increased vulnerability in older adults affected by COVID-19, because it may suggest alterations of physical performance and functional autonomy. Methods: We have conducted a narrative review of the literature on the evidences regarding COVID-19 and the frailty condition. Thirteen observational studies were included. Conclusion: Data emerging from the studies indicate that older COVID-19 patients with a frailty condition have an increased risk of mortality compared with non-frail patients, and this association is independent of other clinical and demographic factors. A frailty evaluation is required to help clinicians to better stratify the overall risk of death for older patients with COVID-19.

Salini, S., Russo, A., De Matteis, G., Piccioni, A., Della Polla, D., Carbone, L., Barillaro, C., Landi, F., Franceschi, F., Covino, M., Frailty in Elderly Patients with Covid-19: A Narrative Review, <<GERONTOLOGY AND GERIATRIC MEDICINE>>, 2022; 8 (8): 1-7. [doi:10.1177/23337214221079956] [http://hdl.handle.net/10807/200104]

Frailty in Elderly Patients with Covid-19: A Narrative Review

Russo A.;De Matteis G.;Piccioni A.;Carbone L.;Barillaro C.;Landi F.;Franceschi F.;Covino M.
2022

Abstract

Introduction: The SARS CoV-2 pandemic still generates a very high number of affected patients and a significant mortality rate. It is essential to establish objective criteria to stratify COVID-19 death risk. Frailty has been identified as a potential determinant of increased vulnerability in older adults affected by COVID-19, because it may suggest alterations of physical performance and functional autonomy. Methods: We have conducted a narrative review of the literature on the evidences regarding COVID-19 and the frailty condition. Thirteen observational studies were included. Conclusion: Data emerging from the studies indicate that older COVID-19 patients with a frailty condition have an increased risk of mortality compared with non-frail patients, and this association is independent of other clinical and demographic factors. A frailty evaluation is required to help clinicians to better stratify the overall risk of death for older patients with COVID-19.
Inglese
Salini, S., Russo, A., De Matteis, G., Piccioni, A., Della Polla, D., Carbone, L., Barillaro, C., Landi, F., Franceschi, F., Covino, M., Frailty in Elderly Patients with Covid-19: A Narrative Review, <>, 2022; 8 (8): 1-7. [doi:10.1177/23337214221079956] [http://hdl.handle.net/10807/200104]
File in questo prodotto:
File Dimensione Formato  
2022 - Frailty in older COVID review.pdf

accesso aperto

Tipologia file ?: Versione Editoriale (PDF)
Licenza: Creative commons
Dimensione 570.52 kB
Formato Adobe PDF
570.52 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/200104
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact