Introduction: The SARS CoV-2 pandemic still generates a very high number of affected patients and a significant mortality rate. It is essential to establish objective criteria to stratify COVID-19 death risk. Frailty has been identified as a potential determinant of increased vulnerability in older adults affected by COVID-19, because it may suggest alterations of physical performance and functional autonomy. Methods: We have conducted a narrative review of the literature on the evidences regarding COVID-19 and the frailty condition. Thirteen observational studies were included. Conclusion: Data emerging from the studies indicate that older COVID-19 patients with a frailty condition have an increased risk of mortality compared with non-frail patients, and this association is independent of other clinical and demographic factors. A frailty evaluation is required to help clinicians to better stratify the overall risk of death for older patients with COVID-19.

Salini, S., Russo, A., De Matteis, G., Piccioni, A., Della Polla, D., Carbone, L., Barillaro, C., Landi, F., Franceschi, F., Covino, M., Frailty in Elderly Patients with Covid-19: A Narrative Review, <<GERONTOLOGY AND GERIATRIC MEDICINE>>, 2022; 8 (8): 1-7. [doi:10.1177/23337214221079956] [http://hdl.handle.net/10807/200104]

Frailty in Elderly Patients with Covid-19: A Narrative Review

Russo, Andrea;De Matteis, Giuseppe;Piccioni, Andrea;Carbone, Luigi;Barillaro, Christian;Landi, Francesco;Franceschi, Francesco;Covino, Marcello
2022

Abstract

Introduction: The SARS CoV-2 pandemic still generates a very high number of affected patients and a significant mortality rate. It is essential to establish objective criteria to stratify COVID-19 death risk. Frailty has been identified as a potential determinant of increased vulnerability in older adults affected by COVID-19, because it may suggest alterations of physical performance and functional autonomy. Methods: We have conducted a narrative review of the literature on the evidences regarding COVID-19 and the frailty condition. Thirteen observational studies were included. Conclusion: Data emerging from the studies indicate that older COVID-19 patients with a frailty condition have an increased risk of mortality compared with non-frail patients, and this association is independent of other clinical and demographic factors. A frailty evaluation is required to help clinicians to better stratify the overall risk of death for older patients with COVID-19.
2022
Inglese
Salini, S., Russo, A., De Matteis, G., Piccioni, A., Della Polla, D., Carbone, L., Barillaro, C., Landi, F., Franceschi, F., Covino, M., Frailty in Elderly Patients with Covid-19: A Narrative Review, <<GERONTOLOGY AND GERIATRIC MEDICINE>>, 2022; 8 (8): 1-7. [doi:10.1177/23337214221079956] [http://hdl.handle.net/10807/200104]
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