An infant with Kawasaki syndrome presenting with fever, rash, and a high percentage of neutrophils with toxic granulation is reported. The peripheral blood smears of the patient showed a high proportion of neutrophils with marked vacuoles and toxic granulations. The reactive changes in neutrophils could be helpful in the early detection of the disease, especially in infants younger than 6 months of age who are at high risk for development of coronary artery disease.
Ruggiero, A., Delogu, A. B., Riccardi, R., Mastrangelo, S., Segni, G., Early reactive neutrophil changes in an infant with Kawasaki syndrome., <<JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY>>, 1999; 21 (4): 303-305. [doi:10.1097/00043426-199907000-00012] [http://hdl.handle.net/10807/19521]
Early reactive neutrophil changes in an infant with Kawasaki syndrome.
Ruggiero, Antonio;Delogu, Angelica Bibiana;Riccardi, Riccardo;Mastrangelo, Stefano;
1999
Abstract
An infant with Kawasaki syndrome presenting with fever, rash, and a high percentage of neutrophils with toxic granulation is reported. The peripheral blood smears of the patient showed a high proportion of neutrophils with marked vacuoles and toxic granulations. The reactive changes in neutrophils could be helpful in the early detection of the disease, especially in infants younger than 6 months of age who are at high risk for development of coronary artery disease.
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