The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
De Carolis, S., Botta, A., Salvi, S., Di Pasquo, E., Del Sordo, G., Garufi, C., Lanzone, A., De Carolis, M. P., Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?, <<AUTOIMMUNITY REVIEWS>>, 2015; 14 (9): 760-762. [doi:10.1016/j.autrev.2015.04.010] [http://hdl.handle.net/10807/192799]
Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?
De Carolis, SaraPrimo
;Botta, AngelaSecondo
;Salvi, Silvia;Lanzone, Antonio;
2015
Abstract
The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
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