Patients treated with interferon alfa can develop autoantibodies and autoimmune diseases. We describe two patients who developed myasthenia gravis with abnormal levels of serum anti-acetylcholine receptor antibodies during interferon alfa-2b treatment for malignancies. One of these patients had myopathic findings on EMG and focal deficiency of cytochrome c oxidase on muscle biopsy.
Batocchi, A. P., Evoli, A., Servidei, S., Palmisani, M., Apollo, F., Tonali, P. A., Myasthenia gravis during interferon alfa therapy, <<NEUROLOGY>>, 1995; 45 (2): 382-383 [http://hdl.handle.net/10807/19016]
Myasthenia gravis during interferon alfa therapy
Batocchi, Anna Paola;Evoli, Amelia;Servidei, Serenella;
1995
Abstract
Patients treated with interferon alfa can develop autoantibodies and autoimmune diseases. We describe two patients who developed myasthenia gravis with abnormal levels of serum anti-acetylcholine receptor antibodies during interferon alfa-2b treatment for malignancies. One of these patients had myopathic findings on EMG and focal deficiency of cytochrome c oxidase on muscle biopsy.
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