Objective/Background. To describe an uncommon, life-threatening condition such as angiosarcoma of a fistula for hemodialysis occurring in a transplant recipient affected by Lowe's syndrome. Summary. We present the case of a 56-year-old male kidney transplant recipient affected by Lowe's syndrome, also known as oculocerebrorenal syndrome, a rare X-linked disorder characterized by congenital cataracts, hypotonia, intellectual disability, and Fanconi-like renal tubular dysfunction, who was diagnosed with angiosarcoma of a functioning arteriovenous fistula for hemodialysis. Conclusion. Angiosarcoma is a rare soft tissue tumor, and only 22 cases of angiosarcoma of arteriovenous fistulae were described so far; although a correlation between Lowe's syndrome and a higher risk of tumor compared to the general population has not been described so far, the mechanisms of disease causation could be an interesting starting point for future studies on a possible connection between the two events.

D'ambrosio, V., Silvestri, P., Aureli, F., Sturniolo, A., Grandaliano, G., Ferraro, P. M., Angiosarcoma of an Arteriovenous Fistula for Hemodialysis in a Kidney Transplant Recipient Affected by Lowe's Syndrome, <<CASE REPORTS IN NEPHROLOGY>>, 2020; 2020 (N/A): N/A-N/A. [doi:10.1155/2020/9734635] [http://hdl.handle.net/10807/181292]

Angiosarcoma of an Arteriovenous Fistula for Hemodialysis in a Kidney Transplant Recipient Affected by Lowe's Syndrome

D'Ambrosio, V.;Silvestri, P.;Aureli, F.;Sturniolo, A.;Grandaliano, G.;Ferraro, P. M.
2020

Abstract

Objective/Background. To describe an uncommon, life-threatening condition such as angiosarcoma of a fistula for hemodialysis occurring in a transplant recipient affected by Lowe's syndrome. Summary. We present the case of a 56-year-old male kidney transplant recipient affected by Lowe's syndrome, also known as oculocerebrorenal syndrome, a rare X-linked disorder characterized by congenital cataracts, hypotonia, intellectual disability, and Fanconi-like renal tubular dysfunction, who was diagnosed with angiosarcoma of a functioning arteriovenous fistula for hemodialysis. Conclusion. Angiosarcoma is a rare soft tissue tumor, and only 22 cases of angiosarcoma of arteriovenous fistulae were described so far; although a correlation between Lowe's syndrome and a higher risk of tumor compared to the general population has not been described so far, the mechanisms of disease causation could be an interesting starting point for future studies on a possible connection between the two events.
Inglese
D'ambrosio, V., Silvestri, P., Aureli, F., Sturniolo, A., Grandaliano, G., Ferraro, P. M., Angiosarcoma of an Arteriovenous Fistula for Hemodialysis in a Kidney Transplant Recipient Affected by Lowe's Syndrome, <<CASE REPORTS IN NEPHROLOGY>>, 2020; 2020 (N/A): N/A-N/A. [doi:10.1155/2020/9734635] [http://hdl.handle.net/10807/181292]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/181292
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