The aim of this manuscript is to analyze an intracranial fluid model from a mathematical point of view. The novel aspect of this work with respect to the existing literature is represented by the rigorous mathematical results regarding the analysis of the solutions to the systems of equations which model the different mechanisms in the cerebrospinal fluid compartments. We are able to prove the existence and uniqueness of a local solution and the existence and uniqueness of a global solution under some restriction conditions on the initial data. Moreover the last part of the paper is devoted to numerical simulations for the analyzed cerebrospinal fluid model. In particular, in order to assess the reliability of the stated theoretical results, we carry out the numerical simulations in two different cases: first, we fix initial data which ,satisfy the conditions for the global existence of solutions, then, we choose initial data that violate them.

Donatelli, D., Marcati, P., Romagnoli, L., Analysis of solutions for a cerebrospinal fluid model, <<NONLINEAR ANALYSIS: REAL WORLD APPLICATIONS>>, 2018; (44): 417-448. [doi:10.1016/j.nonrwa.2018.05.009] [http://hdl.handle.net/10807/176560]

Analysis of solutions for a cerebrospinal fluid model

Romagnoli, Licia
Co-primo
2018

Abstract

The aim of this manuscript is to analyze an intracranial fluid model from a mathematical point of view. The novel aspect of this work with respect to the existing literature is represented by the rigorous mathematical results regarding the analysis of the solutions to the systems of equations which model the different mechanisms in the cerebrospinal fluid compartments. We are able to prove the existence and uniqueness of a local solution and the existence and uniqueness of a global solution under some restriction conditions on the initial data. Moreover the last part of the paper is devoted to numerical simulations for the analyzed cerebrospinal fluid model. In particular, in order to assess the reliability of the stated theoretical results, we carry out the numerical simulations in two different cases: first, we fix initial data which ,satisfy the conditions for the global existence of solutions, then, we choose initial data that violate them.
2018
AREA01 - SCIENZE MATEMATICHE E INFORMATICHE
Articolo su rivista presente in Web of Knowledge o Scopus
Inglese
Articolo in rivista
Inglese
cerebrospinal fluid
fluid dynamics
Settore MAT/05 - ANALISI MATEMATICA
44
2018
417
448
32
Articolo su rivista scientifica / specializzata
a stampa
info:eu-repo/semantics/article
Donatelli, D., Marcati, P., Romagnoli, L., Analysis of solutions for a cerebrospinal fluid model, <<NONLINEAR ANALYSIS: REAL WORLD APPLICATIONS>>, 2018; (44): 417-448. [doi:10.1016/j.nonrwa.2018.05.009] [http://hdl.handle.net/10807/176560]
none
262
Donatelli, Donatella; Marcati, Pierangelo; Romagnoli, Licia
3
art_per_29
03. Contributo in rivista::Articolo in rivista, Nota a sentenza
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/176560
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