Objective: Aortic valve disease is more and more common in western countries. While percutaneous approaches should be preferred in older adults, previous reports have shown good outcomes after surgery. Moreover, advantages of minimally invasive approaches may be valuable for octogenarians. We sought to compare outcomes of conventional aortic valve replacement (CAVR) versus minimally invasive aortic valve replacement (MIAVR) in octogenarians. Methods: We retrospectively collected data of 75 consecutive octogenarians who underwent primary, elective, isolated aortic valve surgery through conventional approach (41 patients, group CAVR) or partial upper sternotomy (34 patients, group MIAVR). Results: Mean age was 81.9 ± 0.9 and 82.3 ± 1.1 years in CAVR and MIAVR patients, respectively (P = 0.09). MIAVR patients had lower 24-hour chest drain output (353.4 ± 207.1 vs 501.7 ± 229.9 mL, P < 0.01), shorter mechanical ventilation (9.6 ± 2.4 vs 11.3 ± 2.3 hours, P < 0.01), lower need for blood transfusions (35.3% vs 63.4%, P = 0.02), and shorter hospital stay (6.8 ± 1.6 vs 8.3 ± 4.3 days, P < 0.01). Thirty-day mortality was zero in both groups. Survival at 1, 3, and 5 years was 89.9%, 80%, and 47%, respectively, in the CAVR group, and 93.2%, 82.4%, and 61.8% in the MIAVR group, with no statistically significant differences (log-rank test, P = 0.35). Conclusions: Aortic valve surgery in older patients provided excellent results, as long as appropriate candidates were selected. MIAVR was associated with shorter mechanical ventilation, reduced blood transfusions, and reduced hospitalization length, without affecting perioperative complications or mid-term survival.

Cammertoni, F., Bruno, P., Rosenhek, R., Pavone, N., Farina, P., Mazza, A., Iafrancesco, M., Nesta, M., Chiariello, G. A., Comerci, G., Pasquini, A., Cavaliere, F., Guarneri, S., Marzetti, E., Rabini, A., Piarulli, A., Sanesi, V., D'errico, D., Massetti, M., Minimally Invasive Aortic Valve Surgery in Octogenarians: Reliable Option or Fallback Solution?, <<INNOVATIONS>>, 2021; (16): 34-42. [doi:10.1177/1556984520974467] [http://hdl.handle.net/10807/173066]

Minimally Invasive Aortic Valve Surgery in Octogenarians: Reliable Option or Fallback Solution?

Cammertoni;P.; Rosenhek;R.; Pavone;N.; Farina;M.; Nesta;M.; Chiariello;G. A.; Comerci;G.; Pasquini;F.; Guarneri;S.; Marzetti;E.; Rabini;A.; Piarulli;A.; Sanesi;D.; Massetti
2021

Abstract

Objective: Aortic valve disease is more and more common in western countries. While percutaneous approaches should be preferred in older adults, previous reports have shown good outcomes after surgery. Moreover, advantages of minimally invasive approaches may be valuable for octogenarians. We sought to compare outcomes of conventional aortic valve replacement (CAVR) versus minimally invasive aortic valve replacement (MIAVR) in octogenarians. Methods: We retrospectively collected data of 75 consecutive octogenarians who underwent primary, elective, isolated aortic valve surgery through conventional approach (41 patients, group CAVR) or partial upper sternotomy (34 patients, group MIAVR). Results: Mean age was 81.9 ± 0.9 and 82.3 ± 1.1 years in CAVR and MIAVR patients, respectively (P = 0.09). MIAVR patients had lower 24-hour chest drain output (353.4 ± 207.1 vs 501.7 ± 229.9 mL, P < 0.01), shorter mechanical ventilation (9.6 ± 2.4 vs 11.3 ± 2.3 hours, P < 0.01), lower need for blood transfusions (35.3% vs 63.4%, P = 0.02), and shorter hospital stay (6.8 ± 1.6 vs 8.3 ± 4.3 days, P < 0.01). Thirty-day mortality was zero in both groups. Survival at 1, 3, and 5 years was 89.9%, 80%, and 47%, respectively, in the CAVR group, and 93.2%, 82.4%, and 61.8% in the MIAVR group, with no statistically significant differences (log-rank test, P = 0.35). Conclusions: Aortic valve surgery in older patients provided excellent results, as long as appropriate candidates were selected. MIAVR was associated with shorter mechanical ventilation, reduced blood transfusions, and reduced hospitalization length, without affecting perioperative complications or mid-term survival.
Inglese
Cammertoni, F., Bruno, P., Rosenhek, R., Pavone, N., Farina, P., Mazza, A., Iafrancesco, M., Nesta, M., Chiariello, G. A., Comerci, G., Pasquini, A., Cavaliere, F., Guarneri, S., Marzetti, E., Rabini, A., Piarulli, A., Sanesi, V., D'errico, D., Massetti, M., Minimally Invasive Aortic Valve Surgery in Octogenarians: Reliable Option or Fallback Solution?, <<INNOVATIONS>>, 2021; (16): 34-42. [doi:10.1177/1556984520974467] [http://hdl.handle.net/10807/173066]
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