Craniopharyngiomas (CPs) are rare benign suprasellar tumors. The standard treatment for CP is complete surgical resection or partial resection followed by adjuvant radiotherapy (RT). Adjuvant RT is typically administered at a total dose of 54 Gy with 1.8 Gy/fraction. The current study reported the case of a young patient affected by recurrent craniopharyngioma, who was treated with irradiation subsequent to several surgical resections. Image fusion and intensity‑modulated radiation therapy techniques were employed to deliver a high total dose (63 Gy with 2.1 Gy/fraction) with no severe acute toxicities recorded. At the 6‑year follow‑up, no radiological or clinical signs of disease progression or late sequelae were observed.

Pierro, A., Cilla, S., Picardi, V., Ferro, M., Macchia, G., Deodato, F., Buwenge, M., Sallustio, G., Morganti, A. G., Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report, <<ONCOLOGY LETTERS>>, 2015; 10 (4): 2491-2494. [doi:10.3892/ol.2015.3514] [http://hdl.handle.net/10807/172261]

Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report

Deodato F.;Sallustio G.;
2015

Abstract

Craniopharyngiomas (CPs) are rare benign suprasellar tumors. The standard treatment for CP is complete surgical resection or partial resection followed by adjuvant radiotherapy (RT). Adjuvant RT is typically administered at a total dose of 54 Gy with 1.8 Gy/fraction. The current study reported the case of a young patient affected by recurrent craniopharyngioma, who was treated with irradiation subsequent to several surgical resections. Image fusion and intensity‑modulated radiation therapy techniques were employed to deliver a high total dose (63 Gy with 2.1 Gy/fraction) with no severe acute toxicities recorded. At the 6‑year follow‑up, no radiological or clinical signs of disease progression or late sequelae were observed.
eng
Pierro, A., Cilla, S., Picardi, V., Ferro, M., Macchia, G., Deodato, F., Buwenge, M., Sallustio, G., Morganti, A. G., Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report, <>, 2015; 10 (4): 2491-2494. [doi:10.3892/ol.2015.3514] [http://hdl.handle.net/10807/172261]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/172261
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