The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

Ciprian Benea, H. R., Earar, K., Lattanzi, W., Quercia, V., Berce, C., Soritau, O., Saccomanno, M., Milano, G., Tomoaia, G., Cerchizan, D., Mohan, A., Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model, <<REVISTA DE CHIMIE>>, 2018; 69 (2): 515-520. [doi:10.37358/rc.18.2.6138] [http://hdl.handle.net/10807/171970]

Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Lattanzi, W.;Saccomanno, M.;Milano, G.;
2018

Abstract

The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.
Inglese
Ciprian Benea, H. R., Earar, K., Lattanzi, W., Quercia, V., Berce, C., Soritau, O., Saccomanno, M., Milano, G., Tomoaia, G., Cerchizan, D., Mohan, A., Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model, <<REVISTA DE CHIMIE>>, 2018; 69 (2): 515-520. [doi:10.37358/rc.18.2.6138] [http://hdl.handle.net/10807/171970]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/171970
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