Objective. A pilot study testing novel ultrasound (US) joint-selection methods in rheumatoid arthritis. Methods. Responsiveness of novel [individualized US (IUS) and individualized composite US (ICUS)] methods were compared with existing US methods and the Disease Activity Score at 28 joints (DAS28) for 12 patients followed for 3 months. IUS selected up to 7 and 12 most ultrasonographically inflamed joints, while ICUS additionally incorporated clinically symptomatic joints. Results. The existing, IUS, and ICUS methods' standardized response means were -0.39, -1.08, and -1.11, respectively, for 7 joints; -0.49, -1.00, and -1.16, respectively, for 12 joints; and -0.94 for DAS28. Conclusion. Novel methods effectively demonstrate inflammatory improvement when compared with existing methods and DAS28.
Tan, Y. K., Allen, J. C., Lye, W. K., Conaghan, P. G., D'Agostino, M. A., Chew, L. -., Thumboo, J., Novel ultrasound joint selection methods using a reduced joint number demonstrate inflammatory improvement when compared to existing methods and disease activity score at 28 joints, <<THE JOURNAL OF RHEUMATOLOGY>>, 2016; 43 (1): 34-37. [doi:10.3899/jrheum.150590] [http://hdl.handle.net/10807/168938]
Novel ultrasound joint selection methods using a reduced joint number demonstrate inflammatory improvement when compared to existing methods and disease activity score at 28 joints
D'Agostino, Maria AntoniettaMembro del Collaboration Group
;
2016
Abstract
Objective. A pilot study testing novel ultrasound (US) joint-selection methods in rheumatoid arthritis. Methods. Responsiveness of novel [individualized US (IUS) and individualized composite US (ICUS)] methods were compared with existing US methods and the Disease Activity Score at 28 joints (DAS28) for 12 patients followed for 3 months. IUS selected up to 7 and 12 most ultrasonographically inflamed joints, while ICUS additionally incorporated clinically symptomatic joints. Results. The existing, IUS, and ICUS methods' standardized response means were -0.39, -1.08, and -1.11, respectively, for 7 joints; -0.49, -1.00, and -1.16, respectively, for 12 joints; and -0.94 for DAS28. Conclusion. Novel methods effectively demonstrate inflammatory improvement when compared with existing methods and DAS28.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.