Objectives: The aim of this study was to evaluate the safety and efficacy of the use of FG-SVFs in face rejuvenation for esthetic improvement. Methods: 33 female patients affected by face’s soft-tissue defects with loss of volume, study group (SG), were treated with FG-SVFs, comparing results with a control group (CG) (n = 30) treated with fat graft not enhanced (FG). Clinical evaluation, a photographic assessment, magnetic resonance imaging (MRI), and ultrasound (US) were performed. Post-operative follow-up was performed at 1, 3, 7, 12, 24, 48, weeks, and then annually. Results: SG patients showed 61% maintenance of the contour restoring and of volume after 3 years compared with the CG treated with FG, who showed 31% maintenance. 60.7% (n = 20) of SG patients, presented an increase of 6.6 mm in the soft tissue volume after 36 months, which was reported in only 33,3% (n = 10) of the CG. Volumetric persistence in the SG was higher than that in the CG (p <. 0001 vs. CG). MRI and US moreover confirmed the absence of important side effects, as fat necrosis, and cytosteatonecrotic areas. Conclusions: The use of FG-SVFs was safe and effective in this series of a case treated.

Gentile, P., Sterodimas, A., Calabrese, C., De Angelis, B., Trivisonno, A., Pizzicannella, J., Dionisi, L., De Fazio, D., Garcovich, S., Regenerative application of stromal vascular fraction cells enhanced fat graft maintenance: clinical assessment in face rejuvenation, <<EXPERT OPINION ON BIOLOGICAL THERAPY>>, 2020; 20 (12): 1503-1513. [doi:10.1080/14712598.2020.1815703] [http://hdl.handle.net/10807/168842]

Regenerative application of stromal vascular fraction cells enhanced fat graft maintenance: clinical assessment in face rejuvenation

Garcovich, Simone
2020

Abstract

Objectives: The aim of this study was to evaluate the safety and efficacy of the use of FG-SVFs in face rejuvenation for esthetic improvement. Methods: 33 female patients affected by face’s soft-tissue defects with loss of volume, study group (SG), were treated with FG-SVFs, comparing results with a control group (CG) (n = 30) treated with fat graft not enhanced (FG). Clinical evaluation, a photographic assessment, magnetic resonance imaging (MRI), and ultrasound (US) were performed. Post-operative follow-up was performed at 1, 3, 7, 12, 24, 48, weeks, and then annually. Results: SG patients showed 61% maintenance of the contour restoring and of volume after 3 years compared with the CG treated with FG, who showed 31% maintenance. 60.7% (n = 20) of SG patients, presented an increase of 6.6 mm in the soft tissue volume after 36 months, which was reported in only 33,3% (n = 10) of the CG. Volumetric persistence in the SG was higher than that in the CG (p <. 0001 vs. CG). MRI and US moreover confirmed the absence of important side effects, as fat necrosis, and cytosteatonecrotic areas. Conclusions: The use of FG-SVFs was safe and effective in this series of a case treated.
2020
Inglese
Gentile, P., Sterodimas, A., Calabrese, C., De Angelis, B., Trivisonno, A., Pizzicannella, J., Dionisi, L., De Fazio, D., Garcovich, S., Regenerative application of stromal vascular fraction cells enhanced fat graft maintenance: clinical assessment in face rejuvenation, <<EXPERT OPINION ON BIOLOGICAL THERAPY>>, 2020; 20 (12): 1503-1513. [doi:10.1080/14712598.2020.1815703] [http://hdl.handle.net/10807/168842]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/168842
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