Introduction: Mini-invasive therapies based on autologous non-activated Platelet-Rich Plasma (ANA-PRP), Low-Level Laser Therapy (LLL-T), and Micro-Needling Technique (MN-T) used in combining for hair re-growth need to be standardized. Objectives: The work aims to show in vivo outcomes resulted from retrospective case-series study in which ANA-PRP + MN-T + LLL-T were used in combined in patients affected by Androgenic alopecia. Methods: 23 patients were treated, of which 13 males were classified in stage I - V by the Norwood–Hamilton scale, and 10 females were classified in stage I - III by the Ludwig scale. Assessment of hair re-growth was evaluated with photography, physician’s and patient’s global assessment scale, and standardized phototrichograms during a follow-up: T0 - baseline, T1 - 12 weeks, T2 - 23 weeks, T3 - 44 weeks, T4 - 58 weeks. Results: Interesting outcomes represented by a hair density increase of 81 ± 5 hairs/cm2 and 57 ± 7 hairs/cm2 respectively at T1 and T2 compared with baseline (173 ± 5 hairs/cm2 at T1 and 149 ± 9 hairs/cm2 at T2 versus 92 ± 2 hairs/cm2 at baseline) were observed using computerized trichograms. Conclusions: The effect of the combined use of MN-T, LLL-T, and ANA-PRP has been demonstrated.

Gentile, P., Dionisi, L., Pizzicannella, J., De Angelis, B., De Fazio, D., Garcovich, S., A Randomized Blinded Retrospective Study: the combined use of Micro-needling Technique, Low-Level Laser Therapy and Autologous Non-Activated Platelet-Rich Plasma improves Hair Re-Growth in patients with Androgenic Alopecia, <<EXPERT OPINION ON BIOLOGICAL THERAPY>>, 2020; 20 (9): 1099-1109-1109. [doi:10.1080/14712598.2020.1797676] [http://hdl.handle.net/10807/168840]

A Randomized Blinded Retrospective Study: the combined use of Micro-needling Technique, Low-Level Laser Therapy and Autologous Non-Activated Platelet-Rich Plasma improves Hair Re-Growth in patients with Androgenic Alopecia

Garcovich, S.
Ultimo
2020

Abstract

Introduction: Mini-invasive therapies based on autologous non-activated Platelet-Rich Plasma (ANA-PRP), Low-Level Laser Therapy (LLL-T), and Micro-Needling Technique (MN-T) used in combining for hair re-growth need to be standardized. Objectives: The work aims to show in vivo outcomes resulted from retrospective case-series study in which ANA-PRP + MN-T + LLL-T were used in combined in patients affected by Androgenic alopecia. Methods: 23 patients were treated, of which 13 males were classified in stage I - V by the Norwood–Hamilton scale, and 10 females were classified in stage I - III by the Ludwig scale. Assessment of hair re-growth was evaluated with photography, physician’s and patient’s global assessment scale, and standardized phototrichograms during a follow-up: T0 - baseline, T1 - 12 weeks, T2 - 23 weeks, T3 - 44 weeks, T4 - 58 weeks. Results: Interesting outcomes represented by a hair density increase of 81 ± 5 hairs/cm2 and 57 ± 7 hairs/cm2 respectively at T1 and T2 compared with baseline (173 ± 5 hairs/cm2 at T1 and 149 ± 9 hairs/cm2 at T2 versus 92 ± 2 hairs/cm2 at baseline) were observed using computerized trichograms. Conclusions: The effect of the combined use of MN-T, LLL-T, and ANA-PRP has been demonstrated.
2020
Inglese
Gentile, P., Dionisi, L., Pizzicannella, J., De Angelis, B., De Fazio, D., Garcovich, S., A Randomized Blinded Retrospective Study: the combined use of Micro-needling Technique, Low-Level Laser Therapy and Autologous Non-Activated Platelet-Rich Plasma improves Hair Re-Growth in patients with Androgenic Alopecia, <<EXPERT OPINION ON BIOLOGICAL THERAPY>>, 2020; 20 (9): 1099-1109-1109. [doi:10.1080/14712598.2020.1797676] [http://hdl.handle.net/10807/168840]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/168840
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 26
social impact