Objective To date, no information on late-onset infection in newborns to mother with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contracted in pregnancy are available. This study aimed to evaluate postdischarge SARS-CoV-2 status of newborns to mothers with COVID-19 in pregnancy that, at birth, were negative to SARS-CoV-2. Study Design This is an observational study of neonates born to mothers with coronavirus disease 2019 (COVID-19). Results Seven pregnant women with documented SARS-CoV-2 infection have been evaluated in our institution. One woman had a spontaneous abortion at 8 weeks of gestational age, four women recovered and are still in follow-up, and two women delivered. Two newborns were enrolled in the study. At birth and 3 days of life, newborns were negative to SARS-CoV-2. At 2-week follow-up, one newborn tested positive although asymptomatic. Conclusion Our findings highlight the importance of follow-up of newborns to mothers with COVID-19 in pregnancy, since they remain at risk of contracting the infection in the early period of life and long-term consequences are still unknown. Key Points Newborns to mothers with coronavirus disease 2019 (COVID-19) in pregnancy can acquire the infection later after birth. Newborns to mothers with COVID-19 in pregnancy need a long-term follow-up, even if they tested negative at birth. Specific guidelines for the long-term follow-up of newborns to mothers with COVID-19 in pregnancy are needed.

Buonsenso, D., Costa, S., Sanguinetti, M., Cattani Franchi, P., Posteraro, B., Marchetti, S., Carducci, B., Lanzone, A., Tamburrini, E., Vento, G., Valentini, P., Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2, <<AMERICAN JOURNAL OF PERINATOLOGY>>, 2020; 37 (8): 869-872. [doi:10.1055/s-0040-1710541] [http://hdl.handle.net/10807/167126]

Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2

Buonsenso, Danilo;Sanguinetti, Maurizio;Cattani Franchi, Paola;Posteraro, Brunella;Marchetti, Simona;Carducci, Brigida;Lanzone, Antonio;Tamburrini, Enrica;Vento, Giovanni;Valentini, Piero
2020

Abstract

Objective To date, no information on late-onset infection in newborns to mother with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contracted in pregnancy are available. This study aimed to evaluate postdischarge SARS-CoV-2 status of newborns to mothers with COVID-19 in pregnancy that, at birth, were negative to SARS-CoV-2. Study Design This is an observational study of neonates born to mothers with coronavirus disease 2019 (COVID-19). Results Seven pregnant women with documented SARS-CoV-2 infection have been evaluated in our institution. One woman had a spontaneous abortion at 8 weeks of gestational age, four women recovered and are still in follow-up, and two women delivered. Two newborns were enrolled in the study. At birth and 3 days of life, newborns were negative to SARS-CoV-2. At 2-week follow-up, one newborn tested positive although asymptomatic. Conclusion Our findings highlight the importance of follow-up of newborns to mothers with COVID-19 in pregnancy, since they remain at risk of contracting the infection in the early period of life and long-term consequences are still unknown. Key Points Newborns to mothers with coronavirus disease 2019 (COVID-19) in pregnancy can acquire the infection later after birth. Newborns to mothers with COVID-19 in pregnancy need a long-term follow-up, even if they tested negative at birth. Specific guidelines for the long-term follow-up of newborns to mothers with COVID-19 in pregnancy are needed.
2020
Inglese
Buonsenso, D., Costa, S., Sanguinetti, M., Cattani Franchi, P., Posteraro, B., Marchetti, S., Carducci, B., Lanzone, A., Tamburrini, E., Vento, G., Valentini, P., Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2, <<AMERICAN JOURNAL OF PERINATOLOGY>>, 2020; 37 (8): 869-872. [doi:10.1055/s-0040-1710541] [http://hdl.handle.net/10807/167126]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/167126
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