Recently, it has been demonstrated that chronic inflammation could have a role on fatigue onset in chronic hemodialysis (HD). Research on neuro-immune interactions highlighted that an alteration of basal ganglia functioning, secondary to chronic inflammation, may translate in a reduced motivation and altered reward processes in chronic diseases. This study investigated a possible correlation between fatigue severity and reward mechanisms, that regulate motivational dispositions, in HD patients. Evaluation scales were administered to ninety-four patients on HD (54 Male, 40 Female; Mdage = 67±26.5; Dialytic Mdage in years = 4±6.3. Fatigue was assessed by using Fatigue Severity Scale (FSS). Behavioural Inhibition System (BIS) and Behavioural Activation System (BAS) Scale was administered to investigate approach/avoidance behaviours. Anxiety and depression were measured by State-Trait Anxiety Inventory (STAI-Y) and Beck Depression Inventory (BDI-II). Results show that the distribution of HD patients for FSS score did not show a normal pattern. FSS score was significantly higher in patients with high BIS Z-score than in patients with low and medium BIS Z-score. BDI score and STAI-Y scores were similar among BIS Z-score groups of patients. Findings suggest that in patients on chronic hemodialysis there is a correlation between fatigue severity symptoms and motivational disposition mechanisms that predispose to action inhibition.

Bossola, M., Angioletti, L., Di Stasio, E., Vulpio, C., De Filippis, D., Balconi, M., Reward (BIS/BAS) mechanisms and fatigue in patients on chronic hemodialysis, <<PSYCHOLOGY, HEALTH & MEDICINE>>, 2020; 25 (6): 710-718. [doi:10.1080/13548506.2019.1653477] [http://hdl.handle.net/10807/165541]

Reward (BIS/BAS) mechanisms and fatigue in patients on chronic hemodialysis

Bossola Maurizio;Angioletti Laura;Di Stasio Enrico;Vulpio Carlo;De Filippis D;Balconi Michela
2020

Abstract

Recently, it has been demonstrated that chronic inflammation could have a role on fatigue onset in chronic hemodialysis (HD). Research on neuro-immune interactions highlighted that an alteration of basal ganglia functioning, secondary to chronic inflammation, may translate in a reduced motivation and altered reward processes in chronic diseases. This study investigated a possible correlation between fatigue severity and reward mechanisms, that regulate motivational dispositions, in HD patients. Evaluation scales were administered to ninety-four patients on HD (54 Male, 40 Female; Mdage = 67±26.5; Dialytic Mdage in years = 4±6.3. Fatigue was assessed by using Fatigue Severity Scale (FSS). Behavioural Inhibition System (BIS) and Behavioural Activation System (BAS) Scale was administered to investigate approach/avoidance behaviours. Anxiety and depression were measured by State-Trait Anxiety Inventory (STAI-Y) and Beck Depression Inventory (BDI-II). Results show that the distribution of HD patients for FSS score did not show a normal pattern. FSS score was significantly higher in patients with high BIS Z-score than in patients with low and medium BIS Z-score. BDI score and STAI-Y scores were similar among BIS Z-score groups of patients. Findings suggest that in patients on chronic hemodialysis there is a correlation between fatigue severity symptoms and motivational disposition mechanisms that predispose to action inhibition.
eng
Bossola, M., Angioletti, L., Di Stasio, E., Vulpio, C., De Filippis, D., Balconi, M., Reward (BIS/BAS) mechanisms and fatigue in patients on chronic hemodialysis, <>, 2020; 25 (6): 710-718. [doi:10.1080/13548506.2019.1653477] [http://hdl.handle.net/10807/165541]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/165541
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