The diagnosis of breast cancer (BC) during pregnancy is uncommon. It has varied among different studies from 1:10,000 to 1:3000 of all pregnancies, with a median age of 33 years. Pregnancy-associated BC represents a challenge in terms of clinical management to guarantee both maternal and fetal security in choosing the right treatment. This situation is complex and requires a multidisciplinary approach, including the surgeon, anesthesiologist, oncologist, radiotherapist, psychologist, and maternal–fetal medicine specialist. In the present review, we examined the management of pregnancy-associated BC, focusing on pathophysiologic background, risk factors, diagnosis, staging procedures, anesthesia, surgical management, and systemic treatment.
Paris, I., Di Giorgio, D., Carbognin, L., Corrado, G., Garganese, G., Franceschini, G., Sanchez, A. M., De Vincenzo, R. P., Accetta, C., Terribile, D. A., Magno, S., Di Leone, A., Bove, S., Masetti, R., Scambia, G., Pregnancy-Associated Breast Cancer: A Multidisciplinary Approach, <<CLINICAL BREAST CANCER>>, 2021; 2021 (S1526-8209(20)): e120-e127. [doi:10.1016/j.clbc.2020.07.007] [https://hdl.handle.net/10807/160990]
Pregnancy-Associated Breast Cancer: A Multidisciplinary Approach
Paris, Ida;Corrado, Giacomo;Garganese, Giorgia;Franceschini, Gianluca;De Vincenzo, Rosa Pasqualina;Terribile, Daniela Andreina;Magno, Stefano;Di Leone, Alba;Masetti, Riccardo;Scambia, Giovanni
2021
Abstract
The diagnosis of breast cancer (BC) during pregnancy is uncommon. It has varied among different studies from 1:10,000 to 1:3000 of all pregnancies, with a median age of 33 years. Pregnancy-associated BC represents a challenge in terms of clinical management to guarantee both maternal and fetal security in choosing the right treatment. This situation is complex and requires a multidisciplinary approach, including the surgeon, anesthesiologist, oncologist, radiotherapist, psychologist, and maternal–fetal medicine specialist. In the present review, we examined the management of pregnancy-associated BC, focusing on pathophysiologic background, risk factors, diagnosis, staging procedures, anesthesia, surgical management, and systemic treatment.
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