COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.
Di Grezia, M., Fransvea, P., Santullo, F., Tirelli, F., Fico, V., Mirco, P., Cozza, V., La Greca, A., Sganga, G., Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function, <<MEDICAL HYPOTHESES>>, 2020; 144 (n/a): 109954-N/A. [doi:10.1016/j.mehy.2020.109954] [http://hdl.handle.net/10807/159060]
Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
Fransvea, Pietro;Tirelli, Flavio;Fico, Valeria;Mirco, Paolo;Cozza, Valerio;La Greca, Antonio;Sganga, Gabriele
2020
Abstract
COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.
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