A young Down's syndrome patient developed tricuspid valve endocarditis several years after undergoing surgical closure of a congenital ventricular septal defect. Fungal etiology was established by PCR amplification of the Candida albicans ERG11 gene. Although antifungal therapy was administered, surgical replacement of the infected valve was required to eliminate the infection.
Posteraro, B., Valentini, P., Delogu, A. B., De Rosa, G., Boccacci, S., Sanguinetti, M., Nacci, A., Miceli Sopo, S., Ranno, O., Morace, G., Fadda, G., Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient, <<SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES>>, 2002; 34 (2): 145-147. [doi:10.1080/00365540110077173] [http://hdl.handle.net/10807/152628]
Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient
Posteraro, Brunella;Valentini, Piero;Delogu, Angelica Bibiana;De Rosa, Gabriella;Sanguinetti, Maurizio;Miceli Sopo, Stefano;Fadda, Guido
2002
Abstract
A young Down's syndrome patient developed tricuspid valve endocarditis several years after undergoing surgical closure of a congenital ventricular septal defect. Fungal etiology was established by PCR amplification of the Candida albicans ERG11 gene. Although antifungal therapy was administered, surgical replacement of the infected valve was required to eliminate the infection.
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