Aim: To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer. Patients and Methods: We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes. Results: Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter. Conclusion: We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
Rausei, S., Galli, F., Lianos, G., Rosa, F., Cossu, A., Biondi, A., Martignoni, F., Cananzi, F. C. M., Fumagalli, U., Alfieri, S., Persiani, R., Quagliuolo, V., D'Ugo, D., Rosati, R., How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion, <<JOURNAL OF GASTROINTESTINAL CANCER>>, 2019; (NA): N/A-N/A. [doi:10.1007/s12029-019-00321-x] [http://hdl.handle.net/10807/147350]
How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion
Rosa, Fausto;Biondi, Alberto;Alfieri, Sergio;Persiani, Roberto;D'Ugo, Domenico;
2019
Abstract
Aim: To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer. Patients and Methods: We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes. Results: Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter. Conclusion: We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
