Preliminary clinical studies with 131I-meta-iodobenzylguanidine, a newly synthesized radiopharmaceutical and guanethidine analog capable of imaging the adrenal medulla, have led to the identification of a case of disseminated malignant pheochromocytoma with the localization of brain and bone metastases. The result is of particular interest as the symptomatology in this case appeared rather equivocal and various investigations had led to a completely different diagnosis. This new scintigraphic technique has proved to be safe, specific and noninvasive, and it may have a clinical application as a complementary or alternative technique to conventional diagnostic tests.

Troncone, L., Maini, C., De Rosa, G., Corsello, S. M., Rufini, V., Mattei, O., Bonifazi, N., Scintigraphic localization of a disseminated malignant pheochromocytoma with the use of 131I-meta-iodobenzylguanidine, <<EUROPEAN JOURNAL OF NUCLEAR MEDICINE>>, 1984; 9 (9): 429-432 [http://hdl.handle.net/10807/13866]

Scintigraphic localization of a disseminated malignant pheochromocytoma with the use of 131I-meta-iodobenzylguanidine

Troncone, Luigi;De Rosa, Giovina;Corsello, Salvatore Maria;Rufini, Vittoria;Mattei, Osvaldo;
1984

Abstract

Preliminary clinical studies with 131I-meta-iodobenzylguanidine, a newly synthesized radiopharmaceutical and guanethidine analog capable of imaging the adrenal medulla, have led to the identification of a case of disseminated malignant pheochromocytoma with the localization of brain and bone metastases. The result is of particular interest as the symptomatology in this case appeared rather equivocal and various investigations had led to a completely different diagnosis. This new scintigraphic technique has proved to be safe, specific and noninvasive, and it may have a clinical application as a complementary or alternative technique to conventional diagnostic tests.
Inglese
Troncone, L., Maini, C., De Rosa, G., Corsello, S. M., Rufini, V., Mattei, O., Bonifazi, N., Scintigraphic localization of a disseminated malignant pheochromocytoma with the use of 131I-meta-iodobenzylguanidine, <<EUROPEAN JOURNAL OF NUCLEAR MEDICINE>>, 1984; 9 (9): 429-432 [http://hdl.handle.net/10807/13866]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/13866
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