Prolonged untreated acromegaly leads to a nonspecific myopathy characterized by ventricular dysfunction and failure. However, the mechanisms responsible for the alterations of cardiac pump function remain to be defined. Because cell death is implicated in most cardiac disease processes, the possibility has been raised that myocyte apoptosis may occur in the acromegalic heart, contributing to the deterioration of ventricular hemodynamics.

Frustaci, A., Chimenti, C., Setoguchi, M., Guerra, S., Corsello, S. M., Crea, F., Leri, A., Kajstura, J., Anversa, P., Maseri, A., Cell death in acromegalic cardiomyopathy, <<CIRCULATION>>, 1999; 99 (11): 1426-1434 [http://hdl.handle.net/10807/13862]

Cell death in acromegalic cardiomyopathy

Frustaci, Andrea;Corsello, Salvatore Maria;Crea, Filippo;
1999

Abstract

Prolonged untreated acromegaly leads to a nonspecific myopathy characterized by ventricular dysfunction and failure. However, the mechanisms responsible for the alterations of cardiac pump function remain to be defined. Because cell death is implicated in most cardiac disease processes, the possibility has been raised that myocyte apoptosis may occur in the acromegalic heart, contributing to the deterioration of ventricular hemodynamics.
1999
Inglese
Frustaci, A., Chimenti, C., Setoguchi, M., Guerra, S., Corsello, S. M., Crea, F., Leri, A., Kajstura, J., Anversa, P., Maseri, A., Cell death in acromegalic cardiomyopathy, <<CIRCULATION>>, 1999; 99 (11): 1426-1434 [http://hdl.handle.net/10807/13862]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/13862
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