Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.

Binda, C., Lopetuso, L. R., Rizzatti, G., Gibiino, G., Cennamo, V., Gasbarrini, A., Actinobacteria: A relevant minority for the maintenance of gut homeostasis, <<DIGESTIVE AND LIVER DISEASE>>, 2018; 50 (5): 421-428. [doi:10.1016/j.dld.2018.02.012] [http://hdl.handle.net/10807/137294]

Actinobacteria: A relevant minority for the maintenance of gut homeostasis

Binda;C.; Lopetuso;L. R.; Rizzatti;G.; Gibiino;G.; Cennamo;V.; Gasbarrini
2018

Abstract

Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.
Inglese
Binda, C., Lopetuso, L. R., Rizzatti, G., Gibiino, G., Cennamo, V., Gasbarrini, A., Actinobacteria: A relevant minority for the maintenance of gut homeostasis, <<DIGESTIVE AND LIVER DISEASE>>, 2018; 50 (5): 421-428. [doi:10.1016/j.dld.2018.02.012] [http://hdl.handle.net/10807/137294]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/137294
Citazioni
  • ???jsp.display-item.citation.pmc??? 100
  • Scopus 204
  • ???jsp.display-item.citation.isi??? 201
social impact