This review will examine the application of genetic analysis to cytological specimens obtained by fine-needle aspiration biopsy in the management of thyroid tumours. In particular, it will consider the use of polymerase chain reaction-based techniques in the diagnosis of the micrometastasis of differentiated thyroid carcinoma to cervical lymph nodes, as well as in the detection of oncogenic alterations in solid thyroid nodules.
Russo, D., Arturi, F., Pontecorvi, A., Filetti, S., Genetic Analysis in Fine-needle Aspiration of the Thyroid: A New Tool for the Clinic, <<TRENDS IN ENDOCRINOLOGY AND METABOLISM>>, 1999; 10 (7): 280-285 [http://hdl.handle.net/10807/13217]
Genetic Analysis in Fine-needle Aspiration of the Thyroid: A New Tool for the Clinic
Pontecorvi, Alfredo;
1999
Abstract
This review will examine the application of genetic analysis to cytological specimens obtained by fine-needle aspiration biopsy in the management of thyroid tumours. In particular, it will consider the use of polymerase chain reaction-based techniques in the diagnosis of the micrometastasis of differentiated thyroid carcinoma to cervical lymph nodes, as well as in the detection of oncogenic alterations in solid thyroid nodules.
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