Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES include the absence of skin or respiratory symptoms of IgE-mediated type. We present four cases that suggest that specific IgEs may have a pathogenic role, resulting in the existence of different FPIES phenotypes. This could be important from a diagnostic and therapeutic point of view.
Miceli Sopo, S., Fantacci, C., Bersani, G., Romano, A., Liotti, L., Monaco, S., Is food protein induced enterocolitis syndrome only a non IgE-mediated food allergy?, <<ALLERGOLOGIA ET IMMUNOPATHOLOGIA>>, 2018; 2018/46 (5): 499-502. [doi:10.1016/j.aller.2017.10.004] [http://hdl.handle.net/10807/130807]
Is food protein induced enterocolitis syndrome only a non IgE-mediated food allergy?
Miceli Sopo, Stefano;Romano, Alberto;
2018
Abstract
Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES include the absence of skin or respiratory symptoms of IgE-mediated type. We present four cases that suggest that specific IgEs may have a pathogenic role, resulting in the existence of different FPIES phenotypes. This could be important from a diagnostic and therapeutic point of view.
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