Excessive alcohol consumption often results in intestinal damage, mediated by inflammatory processes, mainly characterized by an increased influx of leukocytes. Fecal calprotectin is a granulocyte cytosolic protein, representing as a promising marker of subclinical intestinal inflammation. In this study, we assessed fecal calprotectin concentrations (FCCs) in current drinking alcoholics, both at the baseline, and then during a subsequent 84-day period. Moreover, FCCs in the alcoholics were compared with the FCCs in healthy controls.
Montalto, M., Gallo, A., Ferrulli, A., Visca, D., Campobasso, E., Cardone, S., D'Onofrio, F., Santoro, L., Covino, M., Mirijello, A., Leggio, L., Gasbarrini, G. B., Addolorato, G., Fecal calprotectin concentrations in alcoholic patients: a longitudinal study, <<EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY>>, 2011; 23 (1): 76-80. [doi:10.1097/MEG.0b013e32834101f9] [http://hdl.handle.net/10807/12892]
Fecal calprotectin concentrations in alcoholic patients: a longitudinal study
Montalto, Massimo;Gallo, Adele;Ferrulli, Anna;Visca, Dina;Campobasso, Elena;Cardone, Silvia;D'Onofrio, Ferruccio;Santoro, Luca;Covino, Marcello;Mirijello, Antonio;Leggio, Lorenzo;Gasbarrini, Giovanni Battista;Addolorato, Giovanni
2011
Abstract
Excessive alcohol consumption often results in intestinal damage, mediated by inflammatory processes, mainly characterized by an increased influx of leukocytes. Fecal calprotectin is a granulocyte cytosolic protein, representing as a promising marker of subclinical intestinal inflammation. In this study, we assessed fecal calprotectin concentrations (FCCs) in current drinking alcoholics, both at the baseline, and then during a subsequent 84-day period. Moreover, FCCs in the alcoholics were compared with the FCCs in healthy controls.
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