Significantly elevated fractions of diploid hepatocytes and reduction in the polyploid populations have been reported in human and experimentally induced hepatocellular carcinomas (HCC). This study was conducted to determine how these changes are related to conditions that often precede HCC, such as chronic hepatitis, cirrhosis, and premalignant focal nodules in cirrhotic livers.
Anti, M., Marra, G., Rapaccini, G. L., Rumi, C., Bussa, S., Fadda, G., Vecchio, F. M., Valenti, A., Percesepe, A., Pompili, M., DNA ploidy pattern in human chronic liver diseases and hepatic nodular lesions. Flow cytometric analysis on echo-guided needle liver biopsy, <<CANCER>>, 1994; 73 (2): 281-288 [http://hdl.handle.net/10807/12886]
DNA ploidy pattern in human chronic liver diseases and hepatic nodular lesions. Flow cytometric analysis on echo-guided needle liver biopsy
Anti, Marcello;Rapaccini, Gian Ludovico;Rumi, Carlo;Fadda, Guido;Vecchio, Fabio Maria;Pompili, Maurizio
1994
Abstract
Significantly elevated fractions of diploid hepatocytes and reduction in the polyploid populations have been reported in human and experimentally induced hepatocellular carcinomas (HCC). This study was conducted to determine how these changes are related to conditions that often precede HCC, such as chronic hepatitis, cirrhosis, and premalignant focal nodules in cirrhotic livers.
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