Rheumatoid arthritis may cause central nervous system complications by means of various mechanisms. We describe the case of a patient with a new diagnosis of rheumatoid arthritis (RA) complicated by normal-pressure hydrocephalus. After treatment with prednisone, the patient improved remarkably as regards mental status, urinary control and gait. We suggest that normal-pressure hydrocephalus may occur as an extra-articular manifestation of RA, caused by a pathogenic inflammatory mechanism. We analyse previous case reports describing a relationship between RA and normal-pressure hydrocephalus, and discuss potential mechanisms underlying this association
Catananti, C., Mastropaolo, S., Calabrese, C., Silveri, M. C., Onder, G., A case of normal-pressure hydrocephalus associated with rheumatoid arthritis, <<AGING CLINICAL AND EXPERIMENTAL RESEARCH>>, 2010; 2010 (Aprile): 189-191 [http://hdl.handle.net/10807/12808]
A case of normal-pressure hydrocephalus associated with rheumatoid arthritis
Catananti, Chiara;Mastropaolo, Simona;Calabrese, Cristina;Silveri, Maria Caterina;Onder, Graziano
2010
Abstract
Rheumatoid arthritis may cause central nervous system complications by means of various mechanisms. We describe the case of a patient with a new diagnosis of rheumatoid arthritis (RA) complicated by normal-pressure hydrocephalus. After treatment with prednisone, the patient improved remarkably as regards mental status, urinary control and gait. We suggest that normal-pressure hydrocephalus may occur as an extra-articular manifestation of RA, caused by a pathogenic inflammatory mechanism. We analyse previous case reports describing a relationship between RA and normal-pressure hydrocephalus, and discuss potential mechanisms underlying this association
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