The interaction of Fas with FasL has been demonstrated to be implicated in the pathogenesis of several autoimmune and liver diseases. Recently, attention has been focused on the hypothesis that thyrocytes and β cells undergo massive Fas/FasL-mediated apoptosis during autoimmune response. Similarly, hepatocyte cell death occurring following copper accumulation points towards the same mechanism.

Stassi, G., Felice, V. D., Todaro, M., Cappello, F., Zummo, G., Farina, F., Trucco, M., De Maria Marchiano, R., Involvement of Fas/FasL system in the pathogenesis of autoimmune diseases and Wilson's disease, <<ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS>>, 1999; 47 (3): 129-133 [http://hdl.handle.net/10807/114426]

Involvement of Fas/FasL system in the pathogenesis of autoimmune diseases and Wilson's disease

De Maria Marchiano, Ruggero
1999

Abstract

The interaction of Fas with FasL has been demonstrated to be implicated in the pathogenesis of several autoimmune and liver diseases. Recently, attention has been focused on the hypothesis that thyrocytes and β cells undergo massive Fas/FasL-mediated apoptosis during autoimmune response. Similarly, hepatocyte cell death occurring following copper accumulation points towards the same mechanism.
1999
Inglese
Stassi, G., Felice, V. D., Todaro, M., Cappello, F., Zummo, G., Farina, F., Trucco, M., De Maria Marchiano, R., Involvement of Fas/FasL system in the pathogenesis of autoimmune diseases and Wilson's disease, <<ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS>>, 1999; 47 (3): 129-133 [http://hdl.handle.net/10807/114426]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/114426
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 10
  • ???jsp.display-item.citation.isi??? ND
social impact