ACKGROUND/AIM: To report on morbidity and oncological outcomes in a consecutive series of gynecological malignancies involving the vascular district. PATIENTS AND METHODS: We retrospectively evaluated a consecutive series between 1/2015 and 1/2017 with suspicious gynecological malignancies involving the vascular district. Peri-operative data and survival rates were computed. RESULTS: Eight-hundred-four women with gynecological malignancies were admitted for major oncologic surgery during the study period, and among them, 50 cases (6.2%) showed vascular involvement. Twenty-seven and 23 patients were submitted to minor and major vascular procedures, respectively. R0 resection was achieved in 44 patients. There were no perioperative mortalities. Major postoperative complications occurred in 6 patients (12.0%). The 2-year disease free survival (DFS) was 67% if R0 resection was achieved. In patients with positive pathological margins (n=2), the 2-year DFS was 33%. CONCLUSION: Vascular procedures can be safely performed with a proper pre-operative planning and may not be an impediment to major gynecological oncological surgery.
Tinelli, G., Cappuccio, S., Parente, E., Fagotti, A., Gallotta, V., Conte, C., Costantini, B., Gueli Alletti, S., Scambia, G., Vizzielli, G., Resectability and Vascular Management of Retroperitoneal Gynecological Malignancies: A Large Single-institution Case-Series, <<ANTICANCER RESEARCH>>, 2017; 37 (12): 6899-6906. [doi:10.21873/anticanres.12153] [http://hdl.handle.net/10807/112822]
Resectability and Vascular Management of Retroperitoneal Gynecological Malignancies: A Large Single-institution Case-Series
Tinelli, Giovanni;Cappuccio, Serena;Parente, Ezio;Fagotti, Anna;Gallotta, Valerio;Conte, Carmine;Costantini, Barbara;Gueli Alletti, Salvatore;Scambia, Giovanni;Vizzielli, Giuseppe
2017
Abstract
ACKGROUND/AIM: To report on morbidity and oncological outcomes in a consecutive series of gynecological malignancies involving the vascular district. PATIENTS AND METHODS: We retrospectively evaluated a consecutive series between 1/2015 and 1/2017 with suspicious gynecological malignancies involving the vascular district. Peri-operative data and survival rates were computed. RESULTS: Eight-hundred-four women with gynecological malignancies were admitted for major oncologic surgery during the study period, and among them, 50 cases (6.2%) showed vascular involvement. Twenty-seven and 23 patients were submitted to minor and major vascular procedures, respectively. R0 resection was achieved in 44 patients. There were no perioperative mortalities. Major postoperative complications occurred in 6 patients (12.0%). The 2-year disease free survival (DFS) was 67% if R0 resection was achieved. In patients with positive pathological margins (n=2), the 2-year DFS was 33%. CONCLUSION: Vascular procedures can be safely performed with a proper pre-operative planning and may not be an impediment to major gynecological oncological surgery.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.