Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising signature for ameliorating therapy assignment and risk assessment in prostate cancer.
Bonci, D., De Maria Marchiano, R., A predictive signature for therapy assignment and risk assessment in prostate cancer, <<ONCOSCIENCE>>, 2015; 2 (11): 920-923. [doi:10.18632/oncoscience.271] [http://hdl.handle.net/10807/112043]
A predictive signature for therapy assignment and risk assessment in prostate cancer
De Maria Marchiano, Ruggero
2015
Abstract
Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising signature for ameliorating therapy assignment and risk assessment in prostate cancer.
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