PURPOSE: To report 3 cases of stromal rejection after deep anterior lamellar keratoplasty (DALK) assisted by a femtosecond laser. METHODS: Three keratoconus eyes of 2 men (22 and 30 years old) and 1 woman (24 years old) who had DALK with a 60-kHz femtosecond laser developed intrastromal graft rejection with superficial and deep neovascularization after 6, 15, and 12 months, respectively. All patients underwent confocal microscopy and were treated with topical steroid therapy. RESULTS: In vivo confocal microscopy revealed cellular inflammatory infiltrates in the subepithelial and middle stroma of the donor lamella without involvement of the endothelium. Graft rejection was rapidly reversed with topical steroid therapy, and a clear cornea was restored in all cases. CONCLUSIONS: Graft rejection remains a significant complication of lamellar surgery but is associated with good tissue restoration and complete visual recovery.
Mosca, L., Fasciani, R., Mosca, L., Guccione, L., Legrottaglie, E., Siniscalco, A., Riso, M., Balestrazzi, E., Graft rejection after femtosecond laser-assisted deep anterior lamellar keratoplasty: report of 3 cases., <<CORNEA>>, 2011; (Agosto): 912-916 [http://hdl.handle.net/10807/10568]
Graft rejection after femtosecond laser-assisted deep anterior lamellar keratoplasty: report of 3 cases.
Mosca, Luigi;Fasciani, Romina;Mosca, Luca;Guccione, Laura;Siniscalco, Andrea;Riso, Monica;Balestrazzi, Emilio
2011
Abstract
PURPOSE: To report 3 cases of stromal rejection after deep anterior lamellar keratoplasty (DALK) assisted by a femtosecond laser. METHODS: Three keratoconus eyes of 2 men (22 and 30 years old) and 1 woman (24 years old) who had DALK with a 60-kHz femtosecond laser developed intrastromal graft rejection with superficial and deep neovascularization after 6, 15, and 12 months, respectively. All patients underwent confocal microscopy and were treated with topical steroid therapy. RESULTS: In vivo confocal microscopy revealed cellular inflammatory infiltrates in the subepithelial and middle stroma of the donor lamella without involvement of the endothelium. Graft rejection was rapidly reversed with topical steroid therapy, and a clear cornea was restored in all cases. CONCLUSIONS: Graft rejection remains a significant complication of lamellar surgery but is associated with good tissue restoration and complete visual recovery.
| Campo DC | Valore | Lingua |
|---|---|---|
| dc.authority.academicField2000 | Settore MED/30 - MALATTIE APPARATO VISIVO | it |
| dc.authority.ancejournal | CORNEA | it |
| dc.authority.erc2011 | Sensory systems (e.g. visual system, auditory system) | it |
| dc.authority.people | Mosca, Luigi | it |
| dc.authority.people | Fasciani, Romina | it |
| dc.authority.people | Mosca, Luca | it |
| dc.authority.people | Guccione, Laura | it |
| dc.authority.people | Legrottaglie, Ef | - |
| dc.authority.people | Siniscalco, Andrea | it |
| dc.authority.people | Riso, Monica | it |
| dc.authority.people | Balestrazzi, Emilio | it |
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| dc.cilea.flagannuariosi | 8544 | - |
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| dc.cilea.standby | Notification sent at Wed Jun 20 15:09:18 CEST 2012, release date is 2012-06-25 | - |
| dc.collection.id.s | e309db74-00b3-0599-e053-3705fe0a55db | * |
| dc.collection.name | Articolo in rivista, Nota a sentenza | * |
| dc.contributor.faculty | FACOLTA' DI MEDICINA E CHIRURGIA "A.GEMELLI" | * |
| dc.date.accessioned | 2012-06-25T01:04:55Z | - |
| dc.date.available | 2012-06-25T01:04:55Z | - |
| dc.date.issued | 2011 | - |
| dc.description.abstracteng | PURPOSE: To report 3 cases of stromal rejection after deep anterior lamellar keratoplasty (DALK) assisted by a femtosecond laser. METHODS: Three keratoconus eyes of 2 men (22 and 30 years old) and 1 woman (24 years old) who had DALK with a 60-kHz femtosecond laser developed intrastromal graft rejection with superficial and deep neovascularization after 6, 15, and 12 months, respectively. All patients underwent confocal microscopy and were treated with topical steroid therapy. RESULTS: In vivo confocal microscopy revealed cellular inflammatory infiltrates in the subepithelial and middle stroma of the donor lamella without involvement of the endothelium. Graft rejection was rapidly reversed with topical steroid therapy, and a clear cornea was restored in all cases. CONCLUSIONS: Graft rejection remains a significant complication of lamellar surgery but is associated with good tissue restoration and complete visual recovery. | - |
| dc.description.allpeople | Mosca, Luigi; Fasciani, Romina; Mosca, Luca; Guccione, Laura; Legrottaglie, Ef; Siniscalco, Andrea; Riso, Monica; Balestrazzi, Emilio | - |
| dc.description.allpeopleoriginal | Mosca, Luigi; Fasciani, Romina; Mosca, Luca; Guccione, Laura; Legrottaglie, Ef; Siniscalco, Andrea; Riso, Monica; Balestrazzi, Emilio | it |
| dc.description.fulltext | none | en |
| dc.description.fulltextoriginal | none | en |
| dc.description.languageisokeywords | eng | it |
| dc.description.numberofauthors | 8 | - |
| dc.identifier.citation | Mosca, L., Fasciani, R., Mosca, L., Guccione, L., Legrottaglie, E., Siniscalco, A., Riso, M., Balestrazzi, E., Graft rejection after femtosecond laser-assisted deep anterior lamellar keratoplasty: report of 3 cases., <<CORNEA>>, 2011; (Agosto): 912-916 [http://hdl.handle.net/10807/10568] | it |
| dc.identifier.uri | http://hdl.handle.net/10807/10568 | - |
| dc.identifier.url | http://www.corneajrnl.com/ | it |
| dc.language.iso | eng | it |
| dc.relation.firstpage | 912 | it |
| dc.relation.issue | Agosto | it |
| dc.relation.issueyear | 2011 | it |
| dc.relation.lastpage | 916 | it |
| dc.relation.numberofpages | 5 | it |
| dc.subject.keywords | femtosecond laser | it |
| dc.subject.keywords | lamellar keratoplasty | it |
| dc.subject.keywords | graft rejection | it |
| dc.subject.singlekeyword | femtosecond laser | * |
| dc.title | Graft rejection after femtosecond laser-assisted deep anterior lamellar keratoplasty: report of 3 cases. | it |
| dc.type | art_per_29 | - |
| dc.type.contribution | Articolo su rivista scientifica / specializzata | it |
| dc.type.driver | info:eu-repo/semantics/article | - |
| dc.type.full | 03. Contributo in rivista::Articolo in rivista, Nota a sentenza | it |
| dc.type.genius | Pubblicazione su rivista con Impact Factor | - |
| dc.type.miur | 262 | en |
| dc.type.miurarticle | Articolo in rivista | it |
| dc.type.research | AREA06 - SCIENZE MEDICHE | - |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza | |
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