Thirty consecutive Acinetobacter baumannii isolates producing carbapenem-hydrolysing oxacillinases, OXA-23 or OXA-58, were recovered from patients hospitalized in Rome, Italy, between January and November 2007. Among these isolates, two clones not associated with the European clones I or II were observed. The oxacillinase-encoding genes were plasmid- or chromosome-borne. This study reports the dissemination of carbapenem-resistant A. baumannii belonging to two clones among several units in a single hospital and emphasizes the ability of A. baumannii to cause epidemic/endemic outbreaks and also to acquire various resistance genes circulating in the hospital environment.
Mendes, R., Spanu, T., Deshpande, L., Castanheira, M., Jones, R., Fadda, G., . Clonal dissemination of two clusters of Acinetobacter baumannii producing OXA-23 or OXA-58 in Rome, Italy., <<CLINICAL MICROBIOLOGY AND INFECTION>>, 2009; 2009 (Giugno): 588-592 [http://hdl.handle.net/10807/10152]
. Clonal dissemination of two clusters of Acinetobacter baumannii producing OXA-23 or OXA-58 in Rome, Italy.
Spanu, Teresa;Fadda, Giovanni
2009
Abstract
Thirty consecutive Acinetobacter baumannii isolates producing carbapenem-hydrolysing oxacillinases, OXA-23 or OXA-58, were recovered from patients hospitalized in Rome, Italy, between January and November 2007. Among these isolates, two clones not associated with the European clones I or II were observed. The oxacillinase-encoding genes were plasmid- or chromosome-borne. This study reports the dissemination of carbapenem-resistant A. baumannii belonging to two clones among several units in a single hospital and emphasizes the ability of A. baumannii to cause epidemic/endemic outbreaks and also to acquire various resistance genes circulating in the hospital environment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.