Axonal injury causes devastating neural impairment, which is often permanent after central nervous system (CNS) damage. Axon regeneration failure is largely responsible for these long-term deficits and poor functional recovery, and is attributable to cell-intrinsic mechanisms and to the nonpermissive cell-extrinsic environment, which together limit axon regrowth.
Palacios, D., Viscomi, M. T., The intrinsic role of epigenetics in axonal regeneration, in Daniela Palacio, D. P. (ed.), Epigenetics and Regeneration, Elsevier, 125 LONDON WALL, LONDON EC2Y 5AS, ENGLAND 2019: 11 333- 354. 10.1016/B978-0-12-814879-2.00015-7 [http://hdl.handle.net/10807/199546]
The intrinsic role of epigenetics in axonal regeneration
Palacios, Daniela
Primo
;Viscomi, Maria Teresa
Ultimo
2019
Abstract
Axonal injury causes devastating neural impairment, which is often permanent after central nervous system (CNS) damage. Axon regeneration failure is largely responsible for these long-term deficits and poor functional recovery, and is attributable to cell-intrinsic mechanisms and to the nonpermissive cell-extrinsic environment, which together limit axon regrowth.
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