At the example of the MERLIN-Expo case study, important aspects of the documentation and of standardisation of chemical exposure models are discussed. A key challenge faced by developers of large or complex chemical exposure models is limited transparency leading to loss of confidence in the applicability of results of the model and other inefficiencies such as lacking interoperability. These inefficiencies can be addressed by standardisation which is explained as a process leading to improved common definitions, transparency and reliability in application. A review of available frameworks on the documentation of exposure models as well other complex models is conducted. The process of arriving at consensus on recommended documentation of exposure models via a workshop process is described, involving representatives from different stakeholders such as scientists, regulators, manufacturers or consultants. Key components of the documentation of chemical exposure models are presented, and a way to structure the communication of the information is proposed. The role of standardisation in supporting research and innovation projects is illustrated.
Altenpohl, A., Ciffroy, P., Paini, A., Radovnikovic, A., Suciu, N., Tanaka, T., Tediosi, A., Verdonck, F., Handbook of Environmental Chemistry, in Philippe Ciffroy, A. T. E. C. (ed.), Modelling the Fate of Chemicals in the Environment and the Human Body, Springer Verlag, Cham 2018: 59- 76. 10.1007/978-3-319-59502-3_3 [http://hdl.handle.net/10807/111095]
Handbook of Environmental Chemistry
Suciu, Nicoleta;Tanaka, Taku;
2018
Abstract
At the example of the MERLIN-Expo case study, important aspects of the documentation and of standardisation of chemical exposure models are discussed. A key challenge faced by developers of large or complex chemical exposure models is limited transparency leading to loss of confidence in the applicability of results of the model and other inefficiencies such as lacking interoperability. These inefficiencies can be addressed by standardisation which is explained as a process leading to improved common definitions, transparency and reliability in application. A review of available frameworks on the documentation of exposure models as well other complex models is conducted. The process of arriving at consensus on recommended documentation of exposure models via a workshop process is described, involving representatives from different stakeholders such as scientists, regulators, manufacturers or consultants. Key components of the documentation of chemical exposure models are presented, and a way to structure the communication of the information is proposed. The role of standardisation in supporting research and innovation projects is illustrated.
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