Alterations of synaptic transmission induced by inflammatory activity have been linked to the pathogenic mechanisms of multiple sclerosis (MS). Regulated upon activation, normal T-cell expressed, and secreted (RANTES) is a pro-inflammatory chemokine involved in MS pathophysiology, potentially able to regulate glutamate release and plasticity in MS brains, with relevant consequences on the clinical manifestations of the disease.

Mori, F., Nisticò, R., Nicoletti, C., Zagaglia, S., Mandolesi, G., Piccinin, S., Martino, G., Finardi, A., Rossini, P. M., Marfia, G., Furlan, R., Centonze, D., RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis, <<Multiple sclerosis (Houndmills, Basingstoke, England)>>, 2016; (N/A): N/A-N/A. [doi:10.1177/1352458515621796] [http://hdl.handle.net/10807/94465]

RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis

Martino, Gaetano;Rossini, Paolo Maria;
2016

Abstract

Alterations of synaptic transmission induced by inflammatory activity have been linked to the pathogenic mechanisms of multiple sclerosis (MS). Regulated upon activation, normal T-cell expressed, and secreted (RANTES) is a pro-inflammatory chemokine involved in MS pathophysiology, potentially able to regulate glutamate release and plasticity in MS brains, with relevant consequences on the clinical manifestations of the disease.
2016
Inglese
Mori, F., Nisticò, R., Nicoletti, C., Zagaglia, S., Mandolesi, G., Piccinin, S., Martino, G., Finardi, A., Rossini, P. M., Marfia, G., Furlan, R., Centonze, D., RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis, <<Multiple sclerosis (Houndmills, Basingstoke, England)>>, 2016; (N/A): N/A-N/A. [doi:10.1177/1352458515621796] [http://hdl.handle.net/10807/94465]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/94465
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