Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects.

De Simone, C., Perino, F., Caldarola, G., D'Agostino, M., Peris, K., Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports, <<JOURNAL OF INTERNATIONAL MEDICAL RESEARCH>>, 2016; 44 (1_suppl): 67-71. [doi:10.1177/0300060515593250] [http://hdl.handle.net/10807/92635]

Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports

De Simone, Clara
;
Perino, Francesca
Secondo
;
Caldarola, Giacomo;D'Agostino, Magda
Penultimo
;
Peris, Ketty
Ultimo
2016

Abstract

Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects.
2016
Inglese
De Simone, C., Perino, F., Caldarola, G., D'Agostino, M., Peris, K., Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports, <<JOURNAL OF INTERNATIONAL MEDICAL RESEARCH>>, 2016; 44 (1_suppl): 67-71. [doi:10.1177/0300060515593250] [http://hdl.handle.net/10807/92635]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/92635
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