IRIS PubliCatt
PubliCatt è il repository istituzionale ad accesso aperto dell'Università Cattolica del Sacro Cuore, dove gli utenti autorizzati afferenti all'Ateneo provvedono direttamente e autonomamente a depositare e a rendere visibili le proprie pubblicazioni, inserendo i dati descrittivi del documento stesso ("metadati", quali il titolo, autore, abstract, etc.) e, laddove possibile, il testo della pubblicazione stessa (full-text).
PubliCatt utilizza la piattaforma IRIS (Institutional Research Information System) sviluppata da CINECA.
EnglishRelapsing-remitting multiple sclerosis (RRMS), secondary progressive (SP)MS and primary progressive (PP)MS patients showed higher percentages of circulating CD8+CD56-perforin+ T cells than controls whereas only relapsing RRMS and PPMS patients showed higher perforin expression in CD8+CD56- T cells than controls. MS patients with EDSS ≥3 showed higher percentage of CD8+CD56-perforin+ T cells than patients with EDSS <3 and controls whereas patients with EDSS <3 showed higher percentage of this T cell subpopulation than controls. Our data show that MS is characterized by a dysregulation of CD8+CD56-perforin+ T cells that may play a role in the development of disability.
Frisullo, G., Plantone, D., Marti, A., Iorio, R., Nociti, V., Patanella, A. K., Batocchi, A. P., Circulating CD8+CD56-Perforin+ T cells are increased in Multiple Sclerosis patients, <<JOURNAL OF NEUROIMMUNOLOGY>>, 2011; 2011 (Dicembre): 137-141 [http://hdl.handle.net/10807/7772]
| Autori: | ||
| Titolo: | Circulating CD8+CD56-Perforin+ T cells are increased in Multiple Sclerosis patients | |
| Data di pubblicazione: | 2011 | |
| Abstract: | Relapsing-remitting multiple sclerosis (RRMS), secondary progressive (SP)MS and primary progressive (PP)MS patients showed higher percentages of circulating CD8+CD56-perforin+ T cells than controls whereas only relapsing RRMS and PPMS patients showed higher perforin expression in CD8+CD56- T cells than controls. MS patients with EDSS ≥3 showed higher percentage of CD8+CD56-perforin+ T cells than patients with EDSS <3 and controls whereas patients with EDSS <3 showed higher percentage of this T cell subpopulation than controls. Our data show that MS is characterized by a dysregulation of CD8+CD56-perforin+ T cells that may play a role in the development of disability. | |
| Lingua: | Inglese | |
| Rivista: | ||
| Citazione: | Frisullo, G., Plantone, D., Marti, A., Iorio, R., Nociti, V., Patanella, A. K., Batocchi, A. P., Circulating CD8+CD56-Perforin+ T cells are increased in Multiple Sclerosis patients, <<JOURNAL OF NEUROIMMUNOLOGY>>, 2011; 2011 (Dicembre): 137-141 [http://hdl.handle.net/10807/7772] | |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
File in questo prodotto:
Copyright © 2022