Neurological prognostication in comatose survivors of cardiac arrest requires a multimodal approach combining clinical and diagnostic tests. Most patients with good outcomes recover consciousness within 72–120 h of arrest, and therefore the suggested timing for prognostication is 72 h from ROSC, or later. Results of earlier prognostic tests, such as status myoclonus and NSE levels, should also be considered at this time point. A careful clinical neurological examination is the cornerstone of prognostic assessment [and it should be performed after major confounders, (e.g. residual sedation,neuromuscular blockade, metabolic derangements) have been excluded.Although absent or extensormotor responses to pain are not specific for predicting a poor neurological outcome, they are highly sensitive for identifying those patients who require neurological prognostication.

Sandroni, C., Soar, J., Friberg, H., Does this comatose survivor of cardiac arrest have a poor prognosis?, <<INTENSIVE CARE MEDICINE>>, 2016; 42 (1): 104-106. [doi:10.1007/s00134-015-4082-9] [http://hdl.handle.net/10807/72055]

Does this comatose survivor of cardiac arrest have a poor prognosis?

Sandroni, Claudio;
2016

Abstract

Neurological prognostication in comatose survivors of cardiac arrest requires a multimodal approach combining clinical and diagnostic tests. Most patients with good outcomes recover consciousness within 72–120 h of arrest, and therefore the suggested timing for prognostication is 72 h from ROSC, or later. Results of earlier prognostic tests, such as status myoclonus and NSE levels, should also be considered at this time point. A careful clinical neurological examination is the cornerstone of prognostic assessment [and it should be performed after major confounders, (e.g. residual sedation,neuromuscular blockade, metabolic derangements) have been excluded.Although absent or extensormotor responses to pain are not specific for predicting a poor neurological outcome, they are highly sensitive for identifying those patients who require neurological prognostication.
2016
Inglese
Sandroni, C., Soar, J., Friberg, H., Does this comatose survivor of cardiac arrest have a poor prognosis?, <<INTENSIVE CARE MEDICINE>>, 2016; 42 (1): 104-106. [doi:10.1007/s00134-015-4082-9] [http://hdl.handle.net/10807/72055]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/72055
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