In 2004, the World Health Organization defined atypical pituitary adenomas as those with a Ki-67 expression >3%, an excessive p53 expression and increased mitotic activity. As the usefulness of this classification is controversial, we reviewed typical and atypical pituitary adenomas to compare the clinical and prognostic features.
Chiloiro, S., Doglietto, F., Trapasso, B., Iacovazzo, D., Giampietro, A., Di Nardo, F., De Waure, C., Lauriola, L., Mangiola, A., Anile, C., Maira, G., De Marinis, L., Bianchi, A., Typical and Atypical Pituitary Adenomas: A Single-Center Analysis of Outcome and Prognosis, <<NEUROENDOCRINOLOGY>>, 2015; (Gennaio): N/A-N/A. [doi:10.1159/000375448] [http://hdl.handle.net/10807/66767]
Typical and Atypical Pituitary Adenomas: A Single-Center Analysis of Outcome and Prognosis
Chiloiro, Sabrina;Doglietto, Francesco;Iacovazzo, Donato;Giampietro, Antonella;Di Nardo, Francesco;De Waure, Chiara;Lauriola, Libero;Mangiola, Annunziato;Anile, Carmelo;Maira, Giulio;De Marinis, Laura;Bianchi, Antonio
2015
Abstract
In 2004, the World Health Organization defined atypical pituitary adenomas as those with a Ki-67 expression >3%, an excessive p53 expression and increased mitotic activity. As the usefulness of this classification is controversial, we reviewed typical and atypical pituitary adenomas to compare the clinical and prognostic features.
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