Candida mannan (Mn) detection in bronchoalveolar lavage fluid (BALF) was shown to be useful for earlier identification and preemptive therapy targeting in preterm infants at high risk of invasive Candida infection. We investigated whether early detection of Candida Mn in BALF is associated with the presence of some neutrophilic products, as markers of prenatal infection/inflammation.
Vento, G., Lio, A., Tirone, C., Aurilia, C., Tana, M., Piras, A., Ricci, C., Perelli, S., Romagnoli, C., Posteraro, B., Iavarone, F., Cabras, T., Fanali, C., Messana, I., Castagnola, M., Association of high levels of α-defensins and S100A proteins with Candida mannan detection in bronchoalveolar lavage fluid of preterm neonates, <<PEDIATRIC RESEARCH>>, 2013; 74 (1): 19-25. [doi:10.1038/pr.2013.60] [http://hdl.handle.net/10807/53773]
Association of high levels of α-defensins and S100A proteins with Candida mannan detection in bronchoalveolar lavage fluid of preterm neonates
Vento, Giovanni;Lio, Alessandra;Tirone, Chiara;Aurilia, Claudia;Tana, Milena;Piras, Andrea;Romagnoli, Costantino;Posteraro, Brunella;Iavarone, Federica;Cabras, Tiziana;Fanali, Chiara;Messana, Irene;Castagnola, Massimo
2013
Abstract
Candida mannan (Mn) detection in bronchoalveolar lavage fluid (BALF) was shown to be useful for earlier identification and preemptive therapy targeting in preterm infants at high risk of invasive Candida infection. We investigated whether early detection of Candida Mn in BALF is associated with the presence of some neutrophilic products, as markers of prenatal infection/inflammation.
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