Vascular calcification and osteoporosis share similar etiopathogenetic mechanisms. Vitamin K2 deficiency could be responsible of the so called "calcium paradox", that is the lack of calcium in the bone and its storage in the vessel wall. These events may have clinically relevant consequences, such as cardiovascular accidents, and bone fractures.
Flore, R. A., Ponziani, F., Di Rienzo, T., Zocco, M. A., Flex, A., Gerardino, L., Lupascu, A., Santoro, L., Santoliquido, A., Di Stasio, E., Chierici, E., Lanti, A., Tondi, P., Gasbarrini, A., Something more to say about calcium homeostasis: the role of vitamin K2 in vascular calcification and osteoporosis, <<EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES>>, 2013; 17 (18): 2433-2440 [http://hdl.handle.net/10807/52652]
Something more to say about calcium homeostasis: the role of vitamin K2 in vascular calcification and osteoporosis
Flore, Roberto Antonio;Zocco, Maria Assunta;Flex, Andrea;Gerardino, Laura;Lupascu, Andrea;Santoliquido, Angelo;Di Stasio, Enrico;Tondi, Paolo;Gasbarrini, Antonio
2013
Abstract
Vascular calcification and osteoporosis share similar etiopathogenetic mechanisms. Vitamin K2 deficiency could be responsible of the so called "calcium paradox", that is the lack of calcium in the bone and its storage in the vessel wall. These events may have clinically relevant consequences, such as cardiovascular accidents, and bone fractures.
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