We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a Ga-DOTANOC and a F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.

Treglia, G., Salomone, E., Petrone, G., Giaccari, A., Rindi, G., Rufini, V., A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT, <<CLINICAL NUCLEAR MEDICINE>>, 2013; 2013 (N/A): N/A-N/A. [doi:10.1097/RLU.0b013e318279ec68] [http://hdl.handle.net/10807/42573]

A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT

Treglia, Giorgio;Salomone, Enrica;Petrone, Gianluigi;Giaccari, Andrea;Rindi, Guido;Rufini, Vittoria
2013

Abstract

We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a Ga-DOTANOC and a F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.
2013
Inglese
Treglia, G., Salomone, E., Petrone, G., Giaccari, A., Rindi, G., Rufini, V., A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT, <<CLINICAL NUCLEAR MEDICINE>>, 2013; 2013 (N/A): N/A-N/A. [doi:10.1097/RLU.0b013e318279ec68] [http://hdl.handle.net/10807/42573]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/42573
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