The chemiluminescence of peripheral blood monocytes and alveolar macrophages was determined in the presence of luminol and lucigenin, either before or after the cell adherence to the luminometer curvettes. In the case of monocytes, cell adherence induces an increase of luminol-dependent chemiluminescence and has almost no effect on the lucigenin-dependent chemiluminescence. However, it shows a strong inhibition of the lucigenin-dependent chemiluminescence and almost no effect on luminol-dependent chemiluminescence, in the case of alveolar macrophages. These results show that adhesion to plastic alters the metabolic burst of both monocytes and alveolar macrophages. Although the mechanisms are poorly understood, they seem to be related to the modifications that take place during the differentiation of peripheral monocytes to alveolar macrophages.

De Sole, P., Fresu, R., Frigieri, L., Pagliari, G., De Simone, C., Guerriero, C., Effect of adherence to plastic on peripheral blood monocyte and alveolar macrophage chemiluminescence, <<JOURNAL OF BIOLUMINESCENCE AND CHEMILUMINESCENCE>>, 1993; 8 (3): 153-158. [doi:10.1002/bio.1170080305] [http://hdl.handle.net/10807/20212]

Effect of adherence to plastic on peripheral blood monocyte and alveolar macrophage chemiluminescence

De Sole, Pasquale;Pagliari, Gabriella;De Simone, Clara;Guerriero, Cristina
1993

Abstract

The chemiluminescence of peripheral blood monocytes and alveolar macrophages was determined in the presence of luminol and lucigenin, either before or after the cell adherence to the luminometer curvettes. In the case of monocytes, cell adherence induces an increase of luminol-dependent chemiluminescence and has almost no effect on the lucigenin-dependent chemiluminescence. However, it shows a strong inhibition of the lucigenin-dependent chemiluminescence and almost no effect on luminol-dependent chemiluminescence, in the case of alveolar macrophages. These results show that adhesion to plastic alters the metabolic burst of both monocytes and alveolar macrophages. Although the mechanisms are poorly understood, they seem to be related to the modifications that take place during the differentiation of peripheral monocytes to alveolar macrophages.
1993
Inglese
De Sole, P., Fresu, R., Frigieri, L., Pagliari, G., De Simone, C., Guerriero, C., Effect of adherence to plastic on peripheral blood monocyte and alveolar macrophage chemiluminescence, <<JOURNAL OF BIOLUMINESCENCE AND CHEMILUMINESCENCE>>, 1993; 8 (3): 153-158. [doi:10.1002/bio.1170080305] [http://hdl.handle.net/10807/20212]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/20212
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact