Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
Nucera, E., Urbani, S., Buonomo, A., De Pasquale, T. M. A., Rizzi, A., Aruanno, A., Pucci, S., Gadolinium-based contrast agents hypersensitivity: A case series, <<JOURNAL OF ASTHMA AND ALLERGY>>, 2021; 14 (15): 241-244. [doi:10.2147/JAA.S295748] [http://hdl.handle.net/10807/177962]
Gadolinium-based contrast agents hypersensitivity: A case series
Nucera, Eleonora;Urbani, Sara;Buonomo, Alessandro;De Pasquale, Tiziana Maria Angela;Rizzi, Angela;
2021
Abstract
Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
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